RPN1 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RPN1 Polyclonal antibody
Uniprot No.：

P04843
基因名：

RPN1
別名：

D6Wsu137e antibody; Dolichyl diphosphooligosaccharide protein glycosyltransferase 67 kDa subunit antibody; Dolichyl diphosphooligosaccharide protein glycosyltransferase 67 kDa subunit precursor antibody; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit antibody; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 antibody; EC 2.4.1.119 antibody; Oligosaccharyltransferase 1 homolog antibody; oligosaccharyltransferase complex subunit (non-catalytic) antibody; OST1 antibody; RBPH1 antibody; Ribophorin I antibody; Ribophorin-1 antibody; RPN-I antibody; Rpn1 antibody; RPN1_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit protein (44-427AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，RPN1 Antibody (CSB-PA05124A0Rb)，的標記方式是Non-conjugated。對于RPN1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA05124B0Rb	RPN1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA05124C0Rb	RPN1 Antibody, FITC conjugated
Biotin	CSB-PA05124D0Rb	RPN1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
基因功能參考文獻：
1. These results clearly demonstrate that the association of malectin with ribophorin I is required to capture misfolded alpha1-antitrypsin and direct them to the degradation pathway. PMID: 25451265
2. Data indicate that malectin functions by forming a complex with ribophorin I. PMID: 22988243
3. ribophorin I can regulate the delivery of precursor proteins to the OST complex by capturing substrates and presenting them to the catalytic core. PMID: 18607003
亞細胞定位：

Endoplasmic reticulum. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
蛋白家族：

OST1 family
組織特異性：

Expressed in all tissues tested.
數據庫鏈接：

HGNC: 10381

OMIM: 180470

KEGG: hsa:6184

STRING: 9606.ENSP00000296255

UniGene: Hs.518244