REEP2 Recombinant Monoclonal Antibody

中文名稱：

REEP2 Recombinant Monoclonal Antibody
貨號：

CSB-RA299057A0HU
規格：

￥1320
圖片：
Flow cytometric analysis of REEP2 expression in HAP-1 cells using REEP2 antibody. Green, isotype control; red, REEP2.

Western blotting analysis using REEP2 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with REEP2 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
其他：

產品詳情

Uniprot No.：

Q9BRK0
基因名：

REEP2
別名：

REEP2; Receptor Accessory Protein 2; SGC32445; C5orf19; SPG72; Yip2d; Receptor Expression-Enhancing Protein 2; Chromosome 5 Open Reading Frame 19; SPG72A; SPG72B
反應種屬：

Human, Rat
免疫原：

Recombinant Human REEP2 protein
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Monoclonal
抗體亞型：

Rabbit IgG
純化方式：

Affinity-chromatography
克隆號：

3G5
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

ELISA, WB, FC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
FC	1:2000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Flow cytometry (FC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors.
基因功能參考文獻：
1. Expression of the REEP1/REEP2 subfamily appears to be restricted to neuronal and neuronal-like exocytotic tissues, consistent with neuronally restricted symptoms of REEP1 genetic disorders. PMID: 24355597
2. We have identified mutations in REEP2 in two families with relatively pure, early-onset hereditary spastic paraplegia, one with autosomal-dominant and the other with autosomal-recessive transmission. PMID: 24388663
3. In mouse, Reep2 enhances sweet receptor function by a different mechanism than Reep1 uses to enhance olfactory receptor function. PMID: 20943918
相關疾病：

Spastic paraplegia 72 (SPG72)
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

DP1 family
組織特異性：

Detected in brain, heart and skeletal muscle, and at low levels in placenta, kidney and pancreas. Expressed in circumvallate papillae.
數據庫鏈接：

HGNC: 17975

OMIM: 609347

KEGG: hsa:51308

STRING: 9606.ENSP00000254901

UniGene: Hs.416090