MOGS Antibody

產品詳情

Uniprot No.：

Q13724
基因名：

MOGS
別名：

EC 3.2.1.106 antibody; glucosidase I antibody; Mannosyl oligosaccharide glucosidase antibody; Mannosyl-oligosaccharide glucosidase antibody; Mogs antibody; MOGS_HUMAN antibody; Processing A glucosidase I antibody; Processing A-glucosidase I antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human MOGS
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner.
基因功能參考文獻：
1. A shortened immunoglobulin half-life was determined to be the mechanism underlying the hypogammaglobulinemia in congenital disorder of glycosylation type IIb (CDG-IIb). PMID: 24716661
2. Perturbation of free oligosaccharide trafficking in endoplasmic reticulum glucosidase I-deficient and castanospermine-treated cells. PMID: 11942856
3. MafF/NFE2 hetrodimers act as weak transcriptional activators, and, in particular, are able to stimulate activity of the GCS1 promoter. PMID: 12490281
4. identification of sequence motifs responsible for endoplasmic reticulum localization PMID: 12626409
相關疾病：

Type IIb congenital disorder of glycosylation (CDGIIb)
亞細胞定位：

Endoplasmic reticulum membrane; Single-pass type II membrane protein.
蛋白家族：

Glycosyl hydrolase 63 family
數據庫鏈接：

HGNC: 24862

OMIM: 601336

KEGG: hsa:7841

STRING: 9606.ENSP00000233616

UniGene: Hs.516119