LILRB2 Antibody

產品詳情

Uniprot No.：

Q8N423
基因名：

LILRB2
別名：

CD85 antigen-like family member D antibody; CD85d antibody; CD85d antigen antibody; ILT 4 antibody; ILT-4 antibody; ILT4 antibody; Immunoglobulin like transcript 4 antibody; Immunoglobulin-like transcript 4 antibody; Leukocyte immunoglobulin like receptor 2 antibody; Leukocyte immunoglobulin like receptor subfamily B member 2 antibody; Leukocyte immunoglobulin-like receptor 2 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 2 antibody; Leukocyte immunoglobulin-like receptor; subfamily B (with TM and ITIM domains); member 2 antibody; LILRA6 antibody; LILRB2 antibody; LIR 2 antibody; LIR-2 antibody; LIR2 antibody; LIRb antibody; LIRB2_HUMAN antibody; MIR 10 antibody; MIR-10 antibody; MIR10 antibody; Monocyte/macrophage immunoglobulin like receptor 10 antibody; Monocyte/macrophage immunoglobulin-like receptor 10 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human CD85d.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
組織特異性：

Expressed in monocytes and at lower levels in myeloid and plasmacytoid dendritic cells. Expressed in tolerogenic IL10-producing dendritic cells. Expressed in myeloid-derived suppressor cells during pregnancy. Detected at low levels in natural killer (NK)
數據庫鏈接：

HGNC: 6606

OMIM: 604815

STRING: 9606.ENSP00000375629

UniGene: Hs.655652