HERC4 Antibody

產品詳情

Uniprot No.：

Q5GLZ8
基因名：

HERC4
別名：

DKFZP564G092 antibody; HECT and RLD domain containing E3 ubiquitin protein ligase 4 antibody; HECT domain and RCC1 like domain containing protein 4 antibody; HECT domain and RCC1-like domain-containing protein 4 antibody; Hect domain and RLD 4 antibody; HERC 4 antibody; HERC4 antibody; HERC4_HUMAN antibody; KIAA1593 antibody; Probable E3 ubiquitin protein ligase HERC4 antibody; Probable E3 ubiquitin-protein ligase HERC4 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human HERC4
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.
基因功能參考文獻：
1. HERC4 has an effect on the occurrence and development of hepatoma carcinoma PMID: 28430527
2. High HERC4 expression is associated with lung cancer. PMID: 25684480
3. HERC4 ancestor emerged in nematodes and that the family expanded throughout evolution. The mRNA expression pattern of the HERC4 was found to be diverse in selected tissues and cells PMID: 15676274
亞細胞定位：

Cytoplasm, cytosol. Note=shows a punctate cytoplasmic distribution.
組織特異性：

Expressed in brain and testis and detected in heart and placenta.
數據庫鏈接：

HGNC: 24521

OMIM: 609248

KEGG: hsa:26091

STRING: 9606.ENSP00000378624

UniGene: Hs.51891