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  4. Cd46 Antibody

Cd46 Antibody

  • 中文名稱：
    Cd46兔多克隆抗體
  • 貨號：
    CSB-PA004939LA01MO
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Mouse skeletal muscle tissue
      All lanes: Cd46 antibody at 4µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 41, 34 kDa
      Observed band size: 41 kDa
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004939LA01MO at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Mus musculus (Mouse) Cd46 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Cd46 antibody; McpMembrane cofactor protein antibody; CD antigen CD46 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Mouse
  • 免疫原：
    Recombinant Mouse Membrane cofactor protein (45-329AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，Cd46 Antibody (CSB-PA004939LA01MO)，的標記方式是Non-conjugated。對于Cd46 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA004939LB01MO Cd46 Antibody, HRP conjugated ELISA
    FITC CSB-PA004939LC01MO Cd46 Antibody, FITC conjugated
    Biotin CSB-PA004939LD01MO Cd46 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
  • 基因功能參考文獻：
    1. Changes in CD46 expression may lead to changes in VEGF and play a pathologic role in the development of age-related macular degeneration. PMID: 26161984
    2. Our findings provide evidence for expression of CD46 in the mouse eye and a role for CD46 in protection against laser-induced choroidal neovascularization PMID: 25019227
    3. This fusion is mediated by the interaction between viral glycoproteins expressed on the membrane of the infected cells and CD46 on the glial targets, and is also observed using cells expressing recombinant MV glycoproteins. PMID: 15920733
    4. CD46 isoforms function as receptors for human herpesvirus 6 and measles virus PMID: 12171934
    5. Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in sperm and increased male fertility PMID: 12640142
    6. CD46 has a role as a receptor for fusion and entry of human herpesvirus 6 into target cells PMID: 12724329

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  • 亞細胞定位：
    [Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Note=Inner acrosomal membrane of spermatozoa.; [Isoform 2]: Secreted.
  • 組織特異性：
    Present only in testis (at protein level).
  • 數據庫鏈接：