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  4. CPN1 Antibody

CPN1 Antibody

  • 中文名稱：
    CPN1兔多克隆抗體
  • 貨號：
    CSB-PA005898ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: CPN1 antibody at 6.19µg/ml
      Lane 1: Mouse liver tissue
      Lane 2: MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 52 kDa
      Observed band size: 52 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA005898ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA005898ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CPN1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ACBP antibody; Anaphylatoxin inactivator antibody; Arginine carboxypeptidase antibody; Carboxypeptidase N catalytic chain antibody; Carboxypeptidase N polypeptide 1 50 kD antibody; Carboxypeptidase N polypeptide 1 antibody; Carboxypeptidase N small subunit antibody; Carboxypeptidase N subunit 1 antibody; CBPN_HUMAN antibody; CPN antibody; CPN1 antibody; Kininase 1 antibody; Kininase-1 antibody; Kininase1 antibody; Lysine carboxypeptidase antibody; Plasma carboxypeptidase B antibody; SCPN antibody; Serum carboxypeptidase N antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Carboxypeptidase N catalytic chain protein (209-458AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
  • 基因功能參考文獻：
    1. CPN binds to fibrinogen and is present in a fibrin clot prepared from plasma. PMID: 23000409
    2. carboxypeptidase N regulates the biologic activity of SDF-1alpha by reducing the chemokine-specific activity PMID: 15718415
    3. This review summarizes the structure, enzymatic properties and function of this enzyme, including insights gained by the recent elucidation of the crystal structure of the CPN catalytic subunit and structural modeling of the non-catalytic 83 kDa subunit. PMID: 18039526
  • 相關疾病：
    Carboxypeptidase N deficiency (CPND)
  • 亞細胞定位：
    Secreted, extracellular space.
  • 蛋白家族：
    Peptidase M14 family
  • 組織特異性：
    Synthesized in the liver and secreted in plasma.
  • 數據庫鏈接：

    HGNC: 2312

    OMIM: 212070

    KEGG: hsa:1369

    STRING: 9606.ENSP00000359446

    UniGene: Hs.2246