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中文名稱：
ABCB8兔多克隆抗體
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貨號：
CSB-PA033367
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規(guī)格：
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圖片：
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Gel: 6%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA033367(ABCB8 Antibody) at dilution 1/750 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
ABCB8
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別名：
ABCB8; MABC1; MITOSUR; Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial ATP-binding cassette 1; M-ABC1; Mitochondrial sulfonylurea-receptor; MITOSUR
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宿主：
Rabbit
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反應種屬：
Human,Mouse,Rat
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免疫原：
Fusion protein of Human ABCB8
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免疫原種屬：
Homo sapiens (Human)
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標記方式：
Non-conjugated
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抗體亞型：
IgG
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純化方式：
Antigen affinity purification
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：
Liquid
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應用范圍：
ELISA,WB
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推薦稀釋比：
| Application |
Recommended Dilution |
| ELISA |
1:2000-1:5000 |
| WB |
1:500-1:2000 |
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane. Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). Plays a role in mitochondrial iron transport. Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes.
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基因功能參考文獻：
- ABCB8 confers resistance through the protection of mitochondrial DNA from doxorubicin-induced DNA damage in a melanoma cell line. PMID: 19147539
- mutations in ABCB8 and ABCB10 is not associated with acute myeloid leukemia. PMID: 19151771
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亞細胞定位：
Mitochondrion inner membrane; Multi-pass membrane protein.
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蛋白家族：
ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily
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組織特異性：
Ubiquitous.
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數(shù)據(jù)庫鏈接：
Most popular with customers
Gel: 6%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA033367(ABCB8 Antibody) at dilution 1/750 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds
