CD44

CD44是一種細胞表面I型跨膜糖蛋白，屬于黏附分子家族。CD44包括標準亞型（CD44s）和CD44變異亞型（CD44v）。CD44作為一種廣譜表達的細胞粘附分子，參與細胞增殖、分化、遷移，血管生成等生物學過程，對于介導細胞信號轉導，調節組織穩態等功能具有關鍵作用。CD44也被認為是一種整合跨膜糖蛋白，能夠接受細胞微環境的細胞因子的作用，將接收的信號進行整合，通過裂解酶的作用釋放CD44胞內域，將其信號傳到細胞核。CD44也是公認的腫瘤干細胞的標志物，是上皮細胞間充質轉化（EMT）關鍵調節因子，參與腫瘤的發生，進展和轉移。近年來，越來越多的研究發現CD44與多種腫瘤的發生、生長、侵襲、轉移和預后密切相關。

Recombinant Human CD44 活性蛋白實驗驗證數據

High Purity Validated by
SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Measured by its binding ability in a functional ELISA. Immobilized CD44 at 2 μg/ml can bind Anti-CD44 mouse monoclonal antibody(CSB-MA004938A0m, antigen from E.coli), the EC₅₀ of the CD44 protein is 11.89-14.94 ng/ml.

Structure Determined by LC-MS/MS

Based on the SEQUEST from database of Mammalian Cell host and target protein, the LC-MS/MS Analysis result of CSB-MP004938HU(F1) could indicate that this peptide derived from Mammalian Cell-expressed Homo sapiens (Human) CD44.

CD44 Antibody

CD44 Protein

CD44 ELISA Kit

CD44 Antibodies

CD44 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA004938GA01HU	CD44 Antibody	Human,Mouse	ELISA,WB,IHC,IF
CSB-PA644696	CD44 Antibody	Human,Rat	ELISA,WB,IF
CSB-PA135522	Phospho-CD44 (Ser706) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA001460	CD44 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA080035	Phospho-CD44 (S706) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA282285	CD44 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA685145	CD44 Antibody	Human	ELISA,WB
CSB-PA191560	CD44 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-RA004938A0HU	CD44 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC
CSB-MA004938A0m	CD44 Monoclonal Antibody	Human	ELISA, WB, IHC, IF, FC
CSB-MA247417	CD44 Monoclonal Antibody	Human	ELISA, IHC
CSB-RA292372A0HU	CD44 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IF, FC
CSB-RA004938MA1HU	CD44 Recombinant Monoclonal Antibody	Human	ELISA, FC

CD44 Proteins

CD44 Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP004938MO1 CSB-EP004938MO1 CSB-BP004938MO1 CSB-MP004938MO1 CSB-EP004938MO1-B	Recombinant Mouse CD44 antigen (Cd44), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF004938MO	Recombinant Mouse CD44 antigen (Cd44)	in vitro E.coli expression system

CD44 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP004938HU(F1) CSB-BP004938HU(F1) CSB-EP004938HU(F1)-B	Recombinant Human CD44 antigen (CD44), partial	Yeast Baculovirus In Vivo Biotinylation in E.coli
CSB-EP004938HU	Recombinant Human CD44 antigen (CD44), partial	E.coli
CSB-CF004938HU	Recombinant Human CD44 antigen (CD44), partial	in vitro E.coli expression system
CSB-EP004938HU(F1)	Recombinant Human CD44 antigen (CD44), partial	E.coli
CSB-EP004938HU1(F1)	Recombinant Human CD44 antigen (CD44), partial	E.coli
CSB-MP004938HU(F1)	Recombinant Human CD44 antigen (CD44), partial (Active)	Mammalian cell
CSB-MP004938HU(F1)j1-B	Recombinant Human CD44 antigen (CD44), partial,Biotinylated (Active)	Mammalian cell
CSB-EP004938HU(M)a2	Recombinant Human CD44 antigen (CD44) (Δ507-536), partial	E.coli
CSB-EP004938HU2	Recombinant Human CD44 antigen (CD44), partial	E.coli
CSB-MP004938HU3(F1)	Recombinant Human CD44 antigen (CD44), partial	Mammalian cell
CSB-MP004938HU3(F1)d9	Recombinant Human CD44 antigen (CD44), partial	Mammalian cell
CSB-MP004938HU(F3)(M)	Recombinant Human CD44 antigen (CD44)(△476-505aa), partial	Mammalian cell

CD44 Proteins for Rattus norvegicus (Rat)

產品貨號	產品名稱	來源
CSB-YP004938RA1 CSB-EP004938RA1 CSB-BP004938RA1 CSB-MP004938RA1 CSB-EP004938RA1-B	Recombinant Rat CD44 antigen (Cd44), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF004938RA	Recombinant Rat CD44 antigen (Cd44)	in vitro E.coli expression system

CD44 Proteins for Papio hamadryas (Hamadryas baboon)

產品貨號	產品名稱	來源
CSB-YP004938ERJ1 CSB-EP004938ERJ1 CSB-BP004938ERJ1 CSB-MP004938ERJ1 CSB-EP004938ERJ1-B	Recombinant Papio hamadryas CD44 antigen (CD44), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF004938ERJ	Recombinant Papio hamadryas CD44 antigen (CD44)	in vitro E.coli expression system

CD44 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

產品貨號	產品名稱	來源
CSB-YP004938DXU1 CSB-EP004938DXU1 CSB-BP004938DXU1 CSB-MP004938DXU1 CSB-EP004938DXU1-B	Recombinant Cricetulus griseus CD44 antigen (CD44), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF004938DXU	Recombinant Cricetulus griseus CD44 antigen (CD44)	in vitro E.coli expression system

CD44 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產品貨號	產品名稱	來源
CSB-YP635685DO CSB-EP635685DO CSB-BP635685DO CSB-MP635685DO CSB-EP635685DO-B	Recombinant Dog CD44 antigen (CD44), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CD44 Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP643679BO CSB-EP643679BO CSB-BP643679BO CSB-MP643679BO CSB-EP643679BO-B	Recombinant Bovine CD44 antigen (CD44), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CD44 Proteins for Mesocricetus auratus (Golden hamster)

產品貨號	產品名稱	來源
CSB-YP723318MRG CSB-EP723318MRG CSB-BP723318MRG CSB-MP723318MRG CSB-EP723318MRG-B	Recombinant Mesocricetus auratus CD44 antigen (CD44), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli