ANXA2
ANXA2，全名為Annexin A2，是一種鈣依賴性膜結(jié)合蛋白，在細(xì)胞生長和信號轉(zhuǎn)導(dǎo)通路中發(fā)揮重要作用。該蛋白也被稱為Annexin II、Calpactin I heavy chain、Calpactin-1 heavy chain、chromobindin 8、Chromobindin-8、epididymis secretory protein Li 270、Lipocortin II、p36、PAP-IV、Placental anticoagulant protein IV、Protein I等。ANXA2蛋白參與多種細(xì)胞功能，包括囊泡運(yùn)輸、細(xì)胞分裂、鈣信號傳導(dǎo)和細(xì)胞生長。它作為異四聚體發(fā)揮作用，由S100A10/Calb-1等蛋白調(diào)節(jié)其活性。ANXA2蛋白在多種疾病中發(fā)揮作用，如腫瘤、自身免疫性疾病、炎癥性腸病等。近年來，ANXA2蛋白在自身免疫性疾病中的研究越來越引起關(guān)注，認(rèn)為其可能成為多種自身免疫性疾病新的診斷指標(biāo)和治療靶點(diǎn)。此外，ANXA2蛋白還參與熱應(yīng)激反應(yīng)，在細(xì)胞保護(hù)中發(fā)揮重要作用。目前，針對ANXA2蛋白的藥物研發(fā)也在進(jìn)行中，有望為相關(guān)疾病的治療提供新的策略。
熱銷產(chǎn)品
Recombinant Human Annexin A2 (ANXA2) (CSB-EP001840HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ANXA2 Recombinant Monoclonal Antibody (CSB-RA987782A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, PC3 whole cell lysate
All lanes: ANXA2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 39, 41 kDa
Observed band size: 36-45 kDa
IHC image of CSB-RA987782A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
Human Annexin Ⅱ(ANX-Ⅱ) ELISA Kit (CSB-E12156h)
驗(yàn)證數(shù)據(jù)
貨號：CSB-E12156h
規(guī)格：96T/48T
靈敏度：0.098 ng/mL
檢測范圍：0.39 ng/mL-25 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
ANXA2 Antibodies
ANXA2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA01064D0Rb | ANXA2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA001840GA01HU | ANXA2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA01064A0Rb | ANXA2 Antibody | Human | ELISA, WB |
| CSB-MA0106441A0m | ANXA2 Monoclonal Antibody | Human | ELISA,WB,IHC |
| CSB-PA001840HA01HU | ANXA2 Antibody | Human, Mouse | ELISA, WB, IHC, IF, IP |
| CSB-PA001840HD01HU | ANXA2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA548570 | Phospho-ANXA2 (Ser26) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA000879 | ANXA2 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA005132 | ANXA2 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA009119 | Phospho-ANXA2 (S26) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA081479 | ANXA2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA980450 | ANXA2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-RA987782A0HU | ANXA2 Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC |
ANXA2 Proteins
ANXA2 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001840PI CSB-EP001840PI CSB-BP001840PI CSB-MP001840PI CSB-EP001840PI-B |
Recombinant Pig Annexin A2 (ANXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA2 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001840CH CSB-EP001840CH CSB-BP001840CH CSB-MP001840CH CSB-EP001840CH-B |
Recombinant Chicken Annexin A2 (ANXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001840HU CSB-BP001840HU CSB-EP001840HU-B |
Recombinant Human Annexin A2 (ANXA2) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP001840HUe0 | Recombinant Human Annexin A2 (ANXA2) | E.coli |
| CSB-EP001840HU | Recombinant Human Annexin A2 (ANXA2) | E.coli |
| CSB-MP001840HU | Recombinant Human Annexin A2 (ANXA2) | Mammalian cell |
| CSB-EP001840HUa0 | Recombinant Human Annexin A2 (ANXA2) | E.coli |
| CSB-EP001840HUb2 | Recombinant Human Annexin A2 (ANXA2) | E.coli |
ANXA2 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001840BO CSB-EP001840BO CSB-BP001840BO CSB-MP001840BO CSB-EP001840BO-B |
Recombinant Bovine Annexin A2 (ANXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-BP001840MO CSB-EP001840MO-B |
Recombinant Mouse Annexin A2 (Anxa2) | Baculovirus In Vivo Biotinylation in E.coli |
ANXA2 Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001840SH CSB-EP001840SH CSB-BP001840SH CSB-MP001840SH CSB-EP001840SH-B |
Recombinant Sheep Annexin A2 (ANXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA2 Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001840PYX CSB-EP001840PYX CSB-BP001840PYX CSB-MP001840PYX CSB-EP001840PYX-B |
Recombinant Pongo abelii Annexin A2 (ANXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001840DO CSB-EP001840DO CSB-BP001840DO CSB-MP001840DO CSB-EP001840DO-B |
Recombinant Dog Annexin A2 (ANXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA2 Proteins for Cervus elaphus (Red deer)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001840DRN CSB-EP001840DRN CSB-BP001840DRN CSB-MP001840DRN CSB-EP001840DRN-B |
Recombinant Cervus elaphus Annexin A2 (ANXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA2 ELISA Kit
ANXA2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E12156h | Human Annexin Ⅱ(ANX-Ⅱ) ELISA Kit | serum, urine, saliva, cell lysates | 0.098 ng/mL |
