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ANGPT2

ANGPT2(Angiopoietin-2)是一種與血管新生和血管穩定性有關的蛋白質,屬于血管生成調節因子家族。它與另一種相關蛋白質ANGPT1(Angiopoietin-1)共同調節血管系統的功能。ANGPT2主要以溶液中的單體形式存在。ANGPT2可以作為一個抑制因子,阻止新血管的形成。它與ANGPT1相互作用,調控血管內皮細胞的黏附、遷移和生長。這種平衡可以影響血管的穩定性和成熟程度。ANGPT2還可以增加血管通透性,使血管壁變得不穩定,導致血漿成分滲透到周圍組織中。 ANGPT2的異常表達與一些疾病有關,包括癌癥、糖尿病和炎癥性疾病。由于其在血管生成和血管通透性調節中的重要作用,ANGPT2已成為一些藥物開發的靶點,以用于治療與血管系統相關的疾病

更多相關閱讀:血管生成素-2(ANGPT2/Ang-2):首個雙抗眼藥上市,抗腫瘤血管新生潛力靶點!

熱銷產品

Recombinant Human Angiopoietin-2(ANGPT2) (Active) CSB-MP001707HU(A4)

驗證數據

SDS
CSB-MP001707HU(A4) SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
High Purity Validated of CSB-MP001707HU(A4)

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ANGPT2 at 2 μg/ml can bind anti-ANGPT2 recombinant antibody(CSB-RA001707MA01HU), the EC50 is 0.6666-0.8876 ng/mL.

ANGPT2 Recombinant Monoclonal Antibody CSB-RA001707MA01HU

驗證數據

ELISA
High Purity Validated of CSB-RA001707MA01HU

The Binding Activity of ANGPT2 with anti-ANGPT2 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ANGPT2(CSB-MP001707HU(A4)) at 2 μg/mL can bind Anti-ANGPT2 recombinant antibody, the EC50 is 0.6666-0.8876 ng/mL.

ANGPT2 Recombinant Monoclonal Antibody CSB-RA191985A0HU

驗證數據

IHC
CSB-RA191985A0HU IHC

IHC image of CSB-RA191985A0HU diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

IHC
CSB-RA191985A0HU IHC

IHC image of CSB-RA191985A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

ANGPT2 Antibodies

ANGPT2 for Homo sapiens (Human)

ANGPT2 for Mus musculus (Mouse)

ANGPT2 Proteins

ANGPT2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

ANGPT2 Proteins for Mus musculus (Mouse)

ANGPT2 Proteins for Homo sapiens (Human)

ANGPT2 Proteins for Rattus norvegicus (Rat)

ANGPT2 Proteins for Bos taurus (Bovine)

ANGPT2 Proteins for Sus scrofa (Pig)

ANGPT2 ELISA Kit

ANGPT2 ELISA Kit for Homo sapiens (Human)

ANGPT2 ELISA Kit for Mus musculus (Mouse)

ANGPT2 ELISA Kit for Sus scrofa (Pig)

ANGPT2 ELISA Kit for Rattus norvegicus (Rat)