ACKR4是一個編碼非典型趨化因子受體4的基因，屬于G蛋白偶聯(lián)受體家族，并且是C-C型趨化因子的受體。該受體已被證明能夠結(jié)合樹突狀細胞和T細胞活化的趨化因子，包括CCL19/ELC、CCL21/SLC和CCL25/TECK。該基因的一個假基因位于染色體6上。已經(jīng)描述了編碼相同蛋白質(zhì)的可變剪切轉(zhuǎn)錄變體。
ACKR4 is a gene encoding a protein named atypical chemokine receptor 4, which is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described.