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  4. LY6G6D Recombinant Monoclonal Antibody

LY6G6D Recombinant Monoclonal Antibody

  • 中文名稱：
    LY6G6D Recombinant Monoclonal Antibody
  • 貨號(hào)：
    CSB-RA013246MA4HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • The Binding Activity of Macaca fascicularis LY6G6D with Anti-LY6G6D Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis LY6G6D (CSB-YP4607MOV) at 2 μg/mL can bind Anti-LY6G6D recombinant antibody. The EC50 is 19.33-25.47 ng/mL.
    • The Binding Activity of Mouse Ly6g6d with Anti-LY6G6D Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Ly6g6d (CSB-YP4973MO) at 2 μg/mL can bind Anti-LY6G6D recombinant antibody. The EC50 is 5.347-7.161 ng/mL.
    • The Binding Activity of Human LY6G6D with Anti-LY6G6D Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human LY6G6D (CSB-YP013246HU) at 2 μg/mL can bind Anti-LY6G6D recombinant antibody. The EC50 is 10.57-13.27 ng/mL.
    • The Binding Activity of Rat Ly6g6d with Anti-LY6G6D Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Rat Ly6g6d (CSB-YP750592RA) at 2 μg/mL can bind Anti-LY6G6D recombinant antibody. The EC50 is 5.825-7.131 ng/mL.
    • Untransfected HEK-293T cells (green line) and transfected Human LY6G6D HEK-293T stable cells (red line) were stained with anti-LY6G6D antibody (CSB-RA013246MA4MO) (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
    • Untransfected CT26 cells (green line) and transfected Human LY6G6D CT26 stable cells (red line) were stained with anti-LY6G6D antibody (CSB-RA013246MA4MO) (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
    • The purity of LY6G6D was greater than 95% as determined by SEC-HPLC
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CSB-RA013246MA4HU LY6G6D重組單克隆抗體是針對(duì)淋巴細(xì)胞抗原6復(fù)合物G6D（LY6G6D）靶點(diǎn)研發(fā)的高特異性科研工具。LY6G6D屬于LY6/uPAR蛋白家族成員，參與細(xì)胞表面信號(hào)傳導(dǎo)及免疫應(yīng)答調(diào)控，其異常表達(dá)與多種疾病機(jī)制相關(guān)。本產(chǎn)品通過重組技術(shù)制備，具有嚴(yán)格的批次間一致性，經(jīng)多種實(shí)驗(yàn)驗(yàn)證顯示優(yōu)異性能：在ELISA中可精準(zhǔn)檢測(cè)目標(biāo)蛋白，流式細(xì)胞術(shù)（FC）推薦使用1:50-1:200稀釋度，能清晰區(qū)分LY6G6D陽性細(xì)胞群，適用于細(xì)胞表面標(biāo)志物的定性與定量分析。該抗體適用于腫瘤微環(huán)境研究、免疫細(xì)胞亞群分型、受體配體互作機(jī)制探索等科研場(chǎng)景，尤其在探究LY6G6D在免疫調(diào)節(jié)或疾病相關(guān)信號(hào)通路中的作用時(shí)表現(xiàn)突出。其高親和力與低交叉反應(yīng)性設(shè)計(jì)，可為體外細(xì)胞實(shí)驗(yàn)、蛋白質(zhì)互作研究及功能基因組學(xué)提供可靠支持，是基礎(chǔ)研究領(lǐng)域探索LY6G6D生物學(xué)功能的優(yōu)選試劑。
  • Uniprot No.：
  • 基因名：
  • 別名：
    Lymphocyte antigen 6 complex locus protein G6d; Protein Ly6-D; Megakaryocyte-enhanced gene transcript 1 protein; LY6G6D; C6orf23; G6D; MEGT1; NG25
  • 反應(yīng)種屬：
    Human, Mouse, Rat, Macaca fascicularis
  • 免疫原：
    Recombinant Human LY6G6D protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    mIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    9H7
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    FC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. Frequencies of the DRB1, DQA1, DQB1 and TNFA alleles in immigrant population of West Siberia PMID: 19807019
  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Cell projection, filopodium.
  • 組織特異性：
    Expressed in the adult lung, and in fetal liver, lung, kidney, brain and spleen.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13935

    OMIM: 606038

    KEGG: hsa:58530

    STRING: 9606.ENSP00000364985

    UniGene: Hs.591792