PVRIG Antibody, FITC conjugated
產(chǎn)品詳情
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產(chǎn)品名稱：
Rabbit anti-Homo sapiens (Human) PVRIG Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：
PVRIG; C7orf15; Transmembrane protein PVRIG; CD112 receptor; CD112R; Poliovirus receptor-related immunoglobulin domain-containing protein
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宿主：
Rabbit
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反應(yīng)種屬：
Human
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免疫原：
Recombinant Human Transmembrane protein PVRIG protein (193-326AA)
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免疫原種屬：
Homo sapiens (Human)
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標(biāo)記方式：
FITC
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克隆類型：
Polyclonal
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抗體亞型：
IgG
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純化方式：
>95%, Protein G purified
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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產(chǎn)品提供形式：
Liquid
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儲(chǔ)存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點(diǎn)詳情
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功能：
Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
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基因功能參考文獻(xiàn)：
- Blockade of TIGIT or CD112R, separately or together, enhances trastuzumab-triggered antitumor response by human NK cells. PMID: 28623459
- Describe CD112R, a member of poliovirus receptor-like proteins, as a new coinhibitory receptor for T cells. CD112R is preferentially expressed on T cells and inhibits T cell receptor-mediated signals. PMID: 26755705
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亞細(xì)胞定位：
Cell membrane; Multi-pass membrane protein.
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組織特異性：
Expressed in some types of immune cells. Expressed at low levels on the surface of freshly isolated T-cells and natural killer (NK) cells, predominantly on CD8+ T-cells (mainly memory/effector, but not naive cells) and on both CD16+ and CD16- NK cells. T-
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