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Your Good Partner in Biology Research

LTN1 Antibody, Biotin conjugated

  • 中文名稱:
    LTN1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA026646LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LTN1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    LTN1
  • 別名:
    LTN1 antibody; C21orf10 antibody; C21orf98 antibody; KIAA0714 antibody; RNF160 antibody; ZNF294 antibody; HSPC087E3 ubiquitin-protein ligase listerin antibody; EC 2.3.2.27 antibody; RING finger protein 160 antibody; RING-type E3 ubiquitin transferase listerin antibody; Zinc finger protein 294 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human E3 ubiquitin-protein ligase listerin protein (462-591AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product.
  • 基因功能參考文獻:
    1. E3 ligase listerin accesses nascent polypeptides stalled at the Sec61 translocon via a gap in the ribosome-translocon junction near the Sec61 lateral gate. PMID: 25877867
    2. Results show that Listerin specificity for nascent chain-60S complexes depends on nuclear export mediator factor. PMID: 25578875
  • 亞細胞定位:
    Cytoplasm, cytosol.
  • 蛋白家族:
    LTN1 family
  • 數據庫鏈接:

    HGNC: 13082

    OMIM: 613083

    KEGG: hsa:26046

    STRING: 9606.ENSP00000373846

    UniGene: Hs.288773