G Antibody

產(chǎn)品詳情

產(chǎn)品描述：

Immunization of rabbits with the Australian bat lyssavirus (ABLV) glycoprotein (G) produces the anti-serum, which is purified through antigen affinity to get the anti-ABLV G antibody. This G antibody occurs as an IgG. It can react with human samples. And it is available for use in ELISA analysis. The single fusogenic envelope glycoprotein (G), a key determinant of viral neurotropic and neurovirulent properties, mediates the pH-dependent fusion between ABLV and host cells.
Uniprot No.：

Q8JTH0
基因名：

G
別名：

G; Glycoprotein
反應(yīng)種屬：

Human
免疫原：

Human G-CSF-R
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
亞細胞定位：

Virion membrane; Single-pass type I membrane protein.
蛋白家族：

Lyssavirus glycoprotein family