TREM1
TREM1，即髓樣細(xì)胞觸發(fā)受體1，別名CD354、TREM-1。TREM1是一種在中性粒細(xì)胞、單核細(xì)胞和巨噬細(xì)胞表面表達(dá)的髓系細(xì)胞觸發(fā)受體，屬于免疫球蛋白超家族成員。TREM1與DAP12結(jié)合，通過DAP12中的ITAMs（免疫受體酪氨酸激活基序）在酪氨酸殘基上磷酸化，激活下游的ZAP70和SYK蛋白酪氨酸激酶，進(jìn)而通過PI3K、PLC-Gamma和ERK等途徑導(dǎo)致下游信號轉(zhuǎn)導(dǎo)，誘導(dǎo)促炎癥細(xì)胞因子、趨化因子和細(xì)胞表面分子的表達(dá)。TREM1通過進(jìn)一步增加促炎癥細(xì)胞因子的產(chǎn)生來擴(kuò)大Toll樣受體誘導(dǎo)的炎癥，參與調(diào)節(jié)急性和慢性炎癥反應(yīng)，在多種感染性疾病、自身免疫性疾病和腫瘤免疫中發(fā)揮重要作用。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
Western Blot analysis of THP-1 mouse heart cells using TREM-1 Polyclonal Antibody
Human Triggering Receptor Expresses on Myeloid Cells-1,TREM-1 ELISA Kit (CSB-E04836h)
驗(yàn)證數(shù)據(jù)
貨號：CSB-E04836h
規(guī)格：96T/48T
靈敏度：7.81 pg/mL
檢測范圍：31.25 pg/mL-2000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
TREM1 Antibodies
TREM1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA024404GA01HU | TREM1 Antibody | Human | ELISA,WB |
| CSB-PA004863 | TREM1 Antibody | Human | WB, ELISA |
| CSB-PA024404ESR2HU | TREM1 Antibody | Human | ELISA, WB |
TREM1 Proteins
TREM1 Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP024404PYX CSB-EP024404PYX CSB-BP024404PYX CSB-MP024404PYX CSB-EP024404PYX-B |
Recombinant Pongo abelii Triggering receptor expressed on myeloid cells 1 (TREM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TREM1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP024404BO CSB-EP024404BO CSB-BP024404BO CSB-MP024404BO CSB-EP024404BO-B |
Recombinant Bovine Triggering receptor expressed on myeloid cells 1 (TREM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TREM1 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP024404PI CSB-EP024404PI CSB-BP024404PI CSB-MP024404PI CSB-EP024404PI-B |
Recombinant Pig Triggering receptor expressed on myeloid cells 1 (TREM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TREM1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP024404MO CSB-EP024404MO CSB-BP024404MO CSB-MP024404MO CSB-EP024404MO-B |
Recombinant Mouse Triggering receptor expressed on myeloid cells 1 (Trem1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TREM1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP024404HU CSB-EP024404HU CSB-BP024404HU CSB-MP024404HU CSB-EP024404HU-B |
Recombinant Human Triggering receptor expressed on myeloid cells 1 (TREM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TREM1 ELISA Kit
TREM1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04836h | Human Triggering Receptor Expresses on Myeloid Cells-1,TREM-1 ELISA Kit | serum, plasma, tissue homogenates | 7.81 pg/mL |
TREM1 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13848m | Mouse soluble Triggering Receptor Expresses on Myeloid Cells-1,sTREM-1 ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
