TNFRSF9

TNFRSF9，即腫瘤壞死因子受體超家族成員9，別名CD137、4-1BB，是一種I型跨膜蛋白，屬于腫瘤壞死因子受體超家族，主要表達于活化的T細胞表面，也在B細胞、單核細胞和多種轉化細胞系中有表達。
TNFRSF9蛋白與配體4-1BBL（TNFSF9）結合，激活下游的NF-κB信號通路，促進T細胞的克隆增殖、存活和發育。TNFRSF9在免疫應答中發揮關鍵作用，特別是在增強T細胞介導的免疫反應和調節細胞毒性T細胞的活性方面。
TNFRSF9的表達還與多種疾病相關，包括自身免疫疾病和腫瘤等，是免疫治療的潛在靶點。

熱銷產品

Recombinant Human Tumor necrosis factor receptor superfamily member 9 (TNFRSF9), partial (Active) (CSB-MP023984HU1)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized TNFRSF9 at 2 μg/ml can bind TNFSF9（CSB-MP023997HU1）, the EC₅₀ is 1.011-2.429 ng/mL.

TNFRSF9 Antibody (CSB-PA08109A0Rb)

驗證數據

Western Blot
Positive WB detected in: HepG2 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate
All lanes: TNFRSF9 antibody at 2.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 28 kDa
Observed band size: 65 kDa

Immunofluorescent analysis of A549 cells using CSB-PA08109A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

TNFRSF9 Antibody

TNFRSF9 Protein

TNFRSF9 ELISA Kit

TNFRSF9 Antibodies

TNFRSF9 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA011218	TNFRSF9 Antibody	Human	WB, IF, ELISA
CSB-PA983768	TNFRSF9 Antibody	Human	ELISA,IHC
CSB-PA718806	TNFRSF9 Antibody	Human	IHC,ELISA
CSB-PA08109A0Rb	TNFRSF9 Antibody	Human	ELISA, WB, IF
CSB-PA08109B0Rb	TNFRSF9 Antibody, HRP conjugated	Human	ELISA
CSB-PA08109C0Rb	TNFRSF9 Antibody, FITC conjugated	Human
CSB-PA08109D0Rb	TNFRSF9 Antibody, Biotin conjugated	Human	ELISA
CSB-RA023984A1HU	TNFRSF9/4-1BB?Recombinant Monoclonal Antibody	Human	ELISA

TNFRSF9 Proteins

TNFRSF9 Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP023984MO1 CSB-EP023984MO1 CSB-BP023984MO1 CSB-MP023984MO1 CSB-EP023984MO1-B	Recombinant Mouse Tumor necrosis factor receptor superfamily member 9 (Tnfrsf9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023984MO	Recombinant Mouse Tumor necrosis factor receptor superfamily member 9 (Tnfrsf9)	in vitro E.coli expression system

TNFRSF9 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-AP001951HU	Recombinant Human Tumor necrosis factor receptor superfamily member 9 protein (TNFRSF9), partial	E.Coli
CSB-AP005131HU	Recombinant Human Tumor necrosis factor receptor superfamily member 9 (TNFRSF9), partial (Active)	Mammalian cell
CSB-AP005141HU	Recombinant Human Tumor necrosis factor receptor superfamily member 9 (TNFRSF9), partial (Active)	Mammalian cell
CSB-AP005151HU	Recombinant Human Tumor necrosis factor receptor superfamily member 9 (TNFRSF9), partial (Active)	Mammalian cell
CSB-MP023984HU1	Recombinant Human Tumor necrosis factor receptor superfamily member 9 (TNFRSF9), partial (Active)	Mammalian cell