SLC39A6 (Solute Carrier Family 39 Member 6)是一種轉運蛋白，負責將錳、鐵和鋅等離子從細胞外膜運輸?shù)郊毎麅?nèi)。它在人體中廣泛表達，尤其在腦組織中表達水平較高。SLC39A6參與許多生理和病理過程，包括神經(jīng)發(fā)育、免疫調節(jié)、細胞凋亡和代謝調節(jié)等。 近年來的研究發(fā)現(xiàn)，SLC39A6在某些癌癥中的表達水平異常，如乳腺癌、結腸癌、胃癌和前列腺癌等。SLC39A6的過度表達被認為與某些癌癥的發(fā)生和發(fā)展有關，如通過促進癌細胞增殖和轉移。因此，SLC39A6成為了一個重要的癌癥靶點，可以通過調節(jié)SLC39A6的表達和活性，以開發(fā)新的治療癌癥的策略。此外，SLC39A6也被認為是神經(jīng)退行性疾病的潛在治療靶點。

更多SLC39A6相關閱讀：鋅離子轉運蛋白，抗體偶聯(lián)藥物ADC新晉靶點！

熱銷產(chǎn)品

Recombinant Human SLC39A6, partial (Active) (CSB-BP621669HU1)

驗證數(shù)據(jù)

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC39A6 at 1 μg/ml can bind Anti-SLC39A6 recombinant antibody (CSB-RA621669MA1HU), the EC₅₀ is 0.6873-0.9010 ng/mL.

● SLC39A6 Recombinant Monoclonal Antibody CSB-RA621669MA1HU

驗證數(shù)據(jù)

ELISA

The Binding Activity of SLC39A6 with anti-SLC39A6 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC39A6(CSB-BP621669HU) at 1 μg/ml can bind Anti-SLC39A6-1 recombinant antibody, the EC₅₀ is 0.6873-0.9010 ng/mL.