SELE

SELE，即E選擇素，它是一種細胞表面糖蛋白，由SELE基因編碼，主要表達在活化的內(nèi)皮細胞上。SELE的作用機制涉及其在炎癥反應(yīng)中的調(diào)節(jié)作用，特別是在白細胞與內(nèi)皮細胞的粘附過程中。當內(nèi)皮細胞受到炎癥介質(zhì)如腫瘤壞死因子α（TNF-α）或IL-1等刺激時，SELE表達上調(diào)，促進滾動的白細胞粘附于內(nèi)皮細胞表面，并進一步遷移至炎癥部位。SELE的信號通路包括與白細胞表面的配體如sialyl-Lewis X（sLe^X）相互作用，觸發(fā)細胞內(nèi)信號傳導(dǎo)，增強細胞間的粘附。在生物學(xué)意義上，SELE對調(diào)控免疫細胞的遷移、參與炎癥反應(yīng)和免疫監(jiān)視等過程至關(guān)重要。SELE的異常表達與多種病理過程有關(guān)，包括動脈粥樣硬化、炎癥性腸病和自身免疫性疾病等。

熱銷產(chǎn)品

Recombinant Pig E-selectin (SELE), partial (CSB-EP020975PIe1)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

SELE Antibody (CSB-PA056380)

驗證數(shù)據(jù)

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA056380(SELE Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA056380(SELE Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

SELE Antibody

SELE Protein

SELE ELISA Kit

SELE Antibodies

SELE for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA020975GA01HU	SELE Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA056380	SELE Antibody	Human	ELISA,IHC
CSB-PA775739	SELE Antibody	Human	ELISA,IHC
CSB-PA715369	SELE Antibody	Human	WB,ELISA

SELE for Pig

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA020975EA01PI	SELE Antibody	Pig	ELISA
CSB-PA020975EB01PI	SELE Antibody, HRP conjugated	Pig	ELISA
CSB-PA020975EC01PI	SELE Antibody, FITC conjugated	Pig
CSB-PA020975ED01PI	SELE Antibody, Biotin conjugated	Pig	ELISA

SELE Proteins

SELE Proteins for Sus scrofa (Pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP020975PI	Recombinant Pig E-selectin (SELE), partial	Yeast
CSB-EP020975PI	Recombinant Pig E-selectin (SELE), partial	E.coli
CSB-BP020975PI CSB-MP020975PI CSB-EP020975PI-B	Recombinant Pig E-selectin (SELE), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SELE Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP020975BO1 CSB-EP020975BO1 CSB-BP020975BO1 CSB-MP020975BO1 CSB-EP020975BO1-B	Recombinant Bovine E-selectin (SELE), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF020975BO	Recombinant Bovine E-selectin (SELE)	in vitro E.coli expression system

SELE Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP020975HU1 CSB-EP020975HU1 CSB-BP020975HU1 CSB-MP020975HU1 CSB-EP020975HU1-B	Recombinant Human E-selectin (SELE), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF020975HU	Recombinant Human E-selectin (SELE)	in vitro E.coli expression system

SELE Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP020975RB	Recombinant Rabbit E-selectin (SELE), partial	Yeast
CSB-EP020975RB CSB-BP020975RB CSB-MP020975RB CSB-EP020975RB-B	Recombinant Rabbit E-selectin (SELE), partial	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SELE Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP020975DO1 CSB-EP020975DO1 CSB-BP020975DO1 CSB-MP020975DO1 CSB-EP020975DO1-B	Recombinant Dog E-selectin (SELE), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF020975DO	Recombinant Dog E-selectin (SELE)	in vitro E.coli expression system

SELE Proteins for Equus caballus (Horse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP850178HO CSB-EP850178HO CSB-BP850178HO CSB-MP850178HO CSB-EP850178HO-B	Recombinant Horse E-selectin (SELE), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli