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Your Good Partner in Biology Research

SAE1

SAE1,全名為SUMO-激活酶亞基1,也被稱為SUMO-1激活酶E1亞基。它是一種參與蛋白質翻譯后修飾的重要蛋白,通過添加小蛋白SUMO(SUMO1)或sumoylation來調節蛋白質的結構和細胞內定位。SAE1與UBA2蛋白形成一個異二聚體,作為SUMO激活酶,在蛋白質的SUMO化過程中發揮關鍵作用。SAE1蛋白與多種疾病相關,包括奧格登綜合征、成人皮肌炎、肌炎等。在藥物研發方面,針對SAE1蛋白的藥物研究正在進展中,旨在開發新的治療方法來治療與SAE1相關的疾病。

熱銷產品

Recombinant Human SUMO-activating enzyme subunit 1 (SAE1) (CSB-EP883359HU)

驗證數據

CSB-EP883359HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

SAE1 Recombinant Monoclonal Antibody (CSB-RA987582A0HU)

驗證數據

CSB-RA987582A0HU

Western Blot
Positive WB detected in: K562 whole cell lysate
All lanes: SAE1 Antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 39, 30, 34 kDa
Observed band size: 39 kDa

CSB-RA987582A0HU

Immunofluorescence staining of Hela Cells with CSB-RA987582A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

SAE1 Antibodies

SAE1 for Homo sapiens (Human)

SAE1 Proteins

SAE1 Proteins for Bos taurus (Bovine)

SAE1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

SAE1 Proteins for Dictyostelium discoideum (Slime mold)

SAE1 Proteins for Pongo abelii (Sumatran orangutan)

SAE1 Proteins for Rattus norvegicus (Rat)

SAE1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

SAE1 Proteins for Xenopus laevis (African clawed frog)

SAE1 Proteins for Mus musculus (Mouse)

SAE1 Proteins for Homo sapiens (Human)