PRAME
PRAME，全稱為“黑色素瘤優(yōu)先表達(dá)抗原”，是一種在黑色素瘤細(xì)胞中高度表達(dá)的腫瘤相關(guān)抗原。它也被稱為“PRAME蛋白”，在醫(yī)學(xué)研究中，它被用作診斷和鑒別黑色素細(xì)胞腫瘤的可靠標(biāo)記物。PRAME蛋白在正常組織中僅限于睪丸、卵巢、皮脂腺、腎上腺等少數(shù)部位表達(dá)。在藥物研發(fā)方面，PRAME蛋白作為靶點(diǎn)的研究正在推進(jìn)，旨在開發(fā)針對(duì)多種實(shí)體瘤的治療方法。例如，針對(duì)PRAME蛋白的雙特異性抗體和TCR-T細(xì)胞療法在黑色素瘤等癌癥的治療中顯示出潛力。
熱銷產(chǎn)品
Recombinant Human Melanoma antigen preferentially expressed in tumors (PRAME) (CSB-YP018603HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP018603HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) PRAME.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP018603HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) PRAME.
PRAME Antibody (CSB-PA018603LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA018603LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA018603LA01HU at dilution of 1:100
PRAME Antibodies
PRAME for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA018603LA01HU | PRAME Antibody | Human | ELISA, IHC |
| CSB-PA018603LB01HU | PRAME Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018603LC01HU | PRAME Antibody, FITC conjugated | Human | |
| CSB-PA018603LD01HU | PRAME Antibody, Biotin conjugated | Human | ELISA |
PRAME Proteins
PRAME Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018603HU | Recombinant Human Melanoma antigen preferentially expressed in tumors (PRAME) | Yeast |
| CSB-EP018603HU | Recombinant Human Melanoma antigen preferentially expressed in tumors (PRAME) | E.coli |
| CSB-BP018603HU CSB-MP018603HU CSB-EP018603HU-B |
Recombinant Human Melanoma antigen preferentially expressed in tumors (PRAME) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
