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PGAM5

Serine/threonine-protein phosphatase PGAM5, mitochondrial is a protein in humans that is encoded by PGAM5 gene. Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.

PGAM5 Antibodies

PGAM5 for Homo sapiens (Human)

PGAM5 Proteins

PGAM5 Proteins for Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)

PGAM5 Proteins for Drosophila mojavensis (Fruit fly)

PGAM5 Proteins for Drosophila erecta (Fruit fly)

PGAM5 Proteins for Drosophila ananassae (Fruit fly)

PGAM5 Proteins for Drosophila virilis (Fruit fly)

PGAM5 Proteins for Drosophila yakuba (Fruit fly)

PGAM5 Proteins for Drosophila simulans (Fruit fly)

PGAM5 Proteins for Drosophila persimilis (Fruit fly)

PGAM5 Proteins for Drosophila sechellia (Fruit fly)

PGAM5 Proteins for Drosophila willistoni (Fruit fly)

PGAM5 Proteins for Drosophila melanogaster (Fruit fly)

PGAM5 Proteins for Drosophila pseudoobscura pseudoobscura (Fruit fly)

PGAM5 Proteins for Xenopus laevis (African clawed frog)

PGAM5 Proteins for Rattus norvegicus (Rat)

PGAM5 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

PGAM5 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

PGAM5 Proteins for Mus musculus (Mouse)

PGAM5 Proteins for Homo sapiens (Human)