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ORC2

Origin recognition complex subunit 2is a protein in humans that is encoded by ORC2 gene. Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.

ORC2 Antibodies

ORC2 for Homo sapiens (Human)

ORC2 Proteins

ORC2 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

ORC2 Proteins for Bos taurus (Bovine)

ORC2 Proteins for Homo sapiens (Human)

ORC2 Proteins for Drosophila melanogaster (Fruit fly)

ORC2 Proteins for Arabidopsis thaliana (Mouse-ear cress)

ORC2 Proteins for Mus musculus (Mouse)

ORC2 Proteins for Rattus norvegicus (Rat)

ORC2 Proteins for Xenopus laevis (African clawed frog)