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NTMT1

NTMT1,即蛋白質α-N-末端甲基轉移酶1,別名NRMT1、METTL11A。這是一種在蛋白質N末端添加甲基的轉移甲基化酶,已被確定為腫瘤發生和進展的關鍵參與者。NTMT1通過在底物α-N-末端上引入甲基,能夠調節有絲分裂、染色質相互作用、DNA修復和維持基因組穩定性。此外,NTMT1在多種癌癥中過表達,包括黑色素瘤、結直腸癌和宮頸癌,其表達水平與腫瘤的預后和進展有關,表明它在腫瘤發展中的重要作用。

熱銷產品

Recombinant Human N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) (Active) (CSB-EP880111HU1)

驗證數據

CSB-EP880111HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-EP880111HU1

Activity
Measured by its binding ability in a functional ELISA. Immobilized CCL5 at 2 μg/ml can bind human NTMT1, the EC50 of human NTMT1 protein is 3.029-5.404 μg/ml.

NTMT1 Antibody (CSB-PA248105)

驗證數據

CSB-PA248105

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA248105(NTMT1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

NTMT1 Antibodies

NTMT1 for Homo sapiens (Human)

NTMT1 Proteins

NTMT1 Proteins for Homo sapiens (Human)