NRP2

神經(jīng)纖毛蛋白2（NRP2）是一種跨膜糖蛋白，在細(xì)胞表面發(fā)揮多重功能。它通常被稱為neuropilin-2，在多種生理過程中發(fā)揮作用，包括血管生成、神經(jīng)發(fā)育和細(xì)胞遷移。NRP2能夠與多種生長因子和細(xì)胞因子結(jié)合，如血管內(nèi)皮生長因子（VEGF）和神經(jīng)生長因子，從而促進(jìn)血管生成和細(xì)胞遷移。此外，NRP2還參與軸突導(dǎo)向、淋巴管生成、血管發(fā)育及神經(jīng)嵴細(xì)胞遷移等過程。在疾病方面，NRP2的異常表達(dá)與多種癌癥的進(jìn)展、神經(jīng)系統(tǒng)疾病以及心血管疾病相關(guān)。例如，在癌癥中，NRP2的高表達(dá)與腫瘤的侵襲性、轉(zhuǎn)移性和耐藥性增加有關(guān)。在神經(jīng)系統(tǒng)疾病中，NRP2的異常表達(dá)與神經(jīng)退行性疾病和神經(jīng)損傷相關(guān)。在心血管疾病中，NRP2的高表達(dá)與動脈粥樣硬化和血管狹窄相關(guān)。針對NRP2的藥物研發(fā)主要集中在抑制其與VEGF等配體的結(jié)合，以阻斷腫瘤血管生成和細(xì)胞遷移。此外，NRP2也被視為治療自身免疫性疾病和神經(jīng)退行性疾病的潛在靶點。

熱銷產(chǎn)品

NRP2 Antibody (CSB-PA016092LA01HU)

驗證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA016092LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA016092LA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA016092LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Neuropilin-2(NRP2) ELISA kit (CSB-EL016092HU)

驗證數(shù)據(jù)

貨號：CSB-EL016092HU

規(guī)格：96T/48T

靈敏度：0.078 ng/mL

檢測范圍：0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

NRP2 Antibody

NRP2 Protein

NRP2 ELISA Kit

NRP2 Antibodies

NRP2 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA005175	NRP2 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA070153	NRP2 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA255815	NRP2 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA563181	NRP2 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA016092LA01HU	NRP2 Antibody	Human	ELISA, IHC, IF
CSB-PA016092LC01HU	NRP2 Antibody, FITC conjugated	Human
CSB-PA016092LD01HU	NRP2 Antibody, Biotin conjugated	Human	ELISA

NRP2 Proteins

NRP2 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP016092HU CSB-EP016092HU CSB-BP016092HU CSB-MP016092HU CSB-EP016092HU-B	Recombinant Human Neuropilin-2 (NRP2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli