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NOTCH4

Neurogenic locus notch homolog protein 4 is a protein in humans that is encoded by NOTCH4 gene. Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).

NOTCH4 Antibodies

NOTCH4 for Homo sapiens (Human)

NOTCH4 Proteins

NOTCH4 Proteins for Mus musculus (Mouse)

NOTCH4 Proteins for Homo sapiens (Human)