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MCM6

DNA replication licensing factor MCM6 is a protein in humans that is encoded by MCM6 gene. Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

MCM6 Antibodies

MCM6 for Homo sapiens (Human)

MCM6 Proteins

MCM6 Proteins for Mus musculus (Mouse)

MCM6 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

MCM6 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

MCM6 Proteins for Homo sapiens (Human)

MCM6 Proteins for Bos taurus (Bovine)

MCM6 Proteins for Drosophila pseudoobscura pseudoobscura (Fruit fly)

MCM6 Proteins for Rattus norvegicus (Rat)

MCM6 Proteins for Anopheles gambiae (African malaria mosquito)

MCM6 Proteins for Dictyostelium discoideum (Slime mold)

MCM6 Proteins for Drosophila melanogaster (Fruit fly)