日韩在线视频不卡-日一区二区三区-天堂国产+人+综合+亚洲欧美-精品国产一区二区三区久久狼-国产成人无码18禁午夜福利网址-国产在线拍偷自揄拍精品-九色91丨porny丨丝袜-久久天天躁狠狠躁夜夜av-99蜜桃臀久久久欧美精品-成人一区二区视频-狠狠操人人干-40岁干柴烈火少妇高潮不断-国产福利不卡-伊人98-丰满多毛的陰户视频-日韩一二三四五区-国产专区一线二线三线码-好男人社区影院www-国产精品2019-欧美三级一区

Your Good Partner in Biology Research

MAD2L2

Mitotic spindle assembly checkpoint protein MAD2B is a protein in humans that is encoded by MAD2L2 gene. Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.

MAD2L2 Antibodies

MAD2L2 for Homo sapiens (Human)

MAD2L2 Proteins

MAD2L2 Proteins for Rattus norvegicus (Rat)

MAD2L2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

MAD2L2 Proteins for Bos taurus (Bovine)

MAD2L2 Proteins for Gallus gallus (Chicken)

MAD2L2 Proteins for Dictyostelium discoideum (Slime mold)

MAD2L2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

MAD2L2 Proteins for Xenopus laevis (African clawed frog)

MAD2L2 Proteins for Mus musculus (Mouse)

MAD2L2 Proteins for Homo sapiens (Human)