LBR
LBR，全名為lamin B受體，也被稱(chēng)為核纖層蛋白B受體。它在細(xì)胞核膜的內(nèi)層，負(fù)責(zé)將核纖層和異染色質(zhì)錨定在核膜上，對(duì)染色質(zhì)和核纖層蛋白B之間的相互作用至關(guān)重要。LBR蛋白在膽固醇合成過(guò)程中也扮演著關(guān)鍵角色。LBR基因的突變與遺傳性骨骼發(fā)育不良和Greenberg骨骼發(fā)育不良等疾病相關(guān)。目前，針對(duì)LBR蛋白的藥物研發(fā)主要集中在開(kāi)發(fā)抗體和siRNA等治療方法，以治療相關(guān)疾病。
熱銷(xiāo)產(chǎn)品
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA070468(LBR Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: CSB-PA070468(LBR Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
LBR Antibodies
LBR for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA012776GA01HU | LBR Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA070468 | LBR Antibody | Human | ELISA,WB,IHC |
LBR Proteins
LBR Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP613520HU CSB-EP613520HU CSB-BP613520HU CSB-MP613520HU CSB-EP613520HU-B |
Recombinant Human Delta(14)-sterol reductase LBR (LBR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
