IL12B

IL12B，即白細胞介素12β鏈，是一種重要的細胞因子，由活化的巨噬細胞等炎性細胞產生。IL12B與IL12A基因編碼的35 kDα鏈通過二硫鍵連接形成異源二聚體，即具有生物活性的IL-12。其作用機制主要是通過與其受體IL-12R結合，激活JAK-STAT信號轉導通路，特別是通過JAK2/STAT4途徑，促進Th1細胞的分化和活化，增強T細胞和NK細胞產生干擾素-γ(IFN-γ)的能力。IL12B在Th1型免疫應答中發揮關鍵作用，促進細胞介導的免疫反應，對抗細胞內病原體和腫瘤細胞。此外，IL12B的表達和活性還與多發性硬化等自身免疫疾病的發病機制有關。

熱銷產品

Recombinant Human Interleukin-12 subunit beta (IL12B) (CSB-YP011587HU)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

IL12B Recombinant Monoclonal Antibody (CSB-RA895985A0HU)

驗證數據

Overlay Peak curve showing A549 cells stained with CSB-RA895985A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*10⁶cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*10⁶cells) used under the same conditions. Acquisition of >10,000 events was performed.

IL12B Antibody

IL12B Protein

IL12B ELISA Kit

IL12B Antibodies

IL12B for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA011587GA01HU	IL12B Antibody	Human	ELISA,WB
CSB-PA06615A0Rb	IL12B Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA06615B0Rb	IL12B Antibody, HRP conjugated	Human	ELISA
CSB-PA009590	IL12B Antibody	Human	WB, ELISA
CSB-RA895985A0HU	IL12B Recombinant Monoclonal Antibody	Human	ELISA, FC

IL12B for Sheep

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA011587LA01SH	IL12B Antibody	Sheep	ELISA
CSB-PA011587YA01SH	IL12B Antibody	Sheep	ELISA, WB, IHC
CSB-PA011587LD01SH	IL12B Antibody, Biotin conjugated	Sheep	ELISA
CSB-PA011587YD01SH	IL12B Antibody, Biotin conjugated	Sheep	ELISA

IL12B Proteins

IL12B Proteins for Capra hircus (Goat)

產品貨號	產品名稱	來源
CSB-YP011587GO CSB-EP011587GO CSB-BP011587GO CSB-MP011587GO CSB-EP011587GO-B	Recombinant Goat Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Ovis aries (Sheep)

產品貨號	產品名稱	來源
CSB-YP011587SH	Recombinant Sheep Interleukin-12 subunit beta (IL12B)	Yeast
CSB-EP011587SH	Recombinant Sheep Interleukin-12 subunit beta (IL12B)	E.coli
CSB-BP011587SH CSB-MP011587SH CSB-EP011587SH-B	Recombinant Sheep Interleukin-12 subunit beta (IL12B)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP011587MO CSB-EP011587MO CSB-BP011587MO CSB-MP011587MO CSB-EP011587MO-B	Recombinant Mouse Interleukin-12 subunit beta (Il12b)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-BP011587HU CSB-MP011587HU CSB-EP011587HU-B	Recombinant Human Interleukin-12 subunit beta (IL12B)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP011587HU	Recombinant Human Interleukin-12 subunit beta (IL12B)	E.coli
CSB-YP011587HU	Recombinant Human Interleukin-12 subunit beta (IL12B)	Yeast
CSB-EP011587HUc7	Recombinant Human Interleukin-12 subunit beta (IL12B)	E.coli

IL12B Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP011587BO CSB-EP011587BO CSB-BP011587BO CSB-MP011587BO CSB-EP011587BO-B	Recombinant Bovine Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Macaca mulatta (Rhesus macaque)

產品貨號	產品名稱	來源
CSB-YP011587MOW CSB-EP011587MOW CSB-BP011587MOW CSB-MP011587MOW CSB-EP011587MOW-B	Recombinant Macaca mulatta Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Felis catus (Cat) (Felis silvestris catus)

產品貨號	產品名稱	來源
CSB-YP011587CA CSB-EP011587CA CSB-BP011587CA CSB-MP011587CA CSB-EP011587CA-B	Recombinant Cat Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

產品貨號	產品名稱	來源
CSB-YP011587DRI CSB-EP011587DRI CSB-BP011587DRI CSB-MP011587DRI CSB-EP011587DRI-B	Recombinant Cercocebus atys Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Cervus elaphus (Red deer)

產品貨號	產品名稱	來源
CSB-YP631703DRN CSB-EP631703DRN CSB-BP631703DRN CSB-MP631703DRN CSB-EP631703DRN-B	Recombinant Cervus elaphus Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產品貨號	產品名稱	來源
CSB-YP632962DO CSB-EP632962DO CSB-BP632962DO CSB-MP632962DO CSB-EP632962DO-B	Recombinant Dog Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Sus scrofa (Pig)

產品貨號	產品名稱	來源
CSB-YP637926PI CSB-EP637926PI CSB-BP637926PI CSB-MP637926PI CSB-EP637926PI-B	Recombinant Pig Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

產品貨號	產品名稱	來源
CSB-YP652387BAAW CSB-EP652387BAAW CSB-BP652387BAAW CSB-MP652387BAAW CSB-EP652387BAAW-B	Recombinant Bubalus carabanensis Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Marmota monax (Woodchuck)

產品貨號	產品名稱	來源
CSB-YP726757MQG CSB-EP726757MQG CSB-BP726757MQG CSB-MP726757MQG CSB-EP726757MQG-B	Recombinant Marmota monax Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Bubalus bubalis (Domestic water buffalo)

產品貨號	產品名稱	來源
CSB-YP769698BWX CSB-EP769698BWX CSB-BP769698BWX CSB-MP769698BWX CSB-EP769698BWX-B	Recombinant Bubalus bubalis Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Lama glama (Llama)

產品貨號	產品名稱	來源
CSB-YP771277LBS CSB-EP771277LBS CSB-BP771277LBS CSB-MP771277LBS CSB-EP771277LBS-B	Recombinant Lama glama Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Papio anubis (Olive baboon)

產品貨號	產品名稱	來源
CSB-YP803041ERI CSB-EP803041ERI CSB-BP803041ERI CSB-MP803041ERI CSB-EP803041ERI-B	Recombinant Papio anubis Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Mesocricetus auratus (Golden hamster)

產品貨號	產品名稱	來源
CSB-YP817228MRG CSB-BP817228MRG CSB-MP817228MRG CSB-EP817228MRG-B	Recombinant Mesocricetus auratus Interleukin-12 subunit beta (IL12B)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Cavia porcellus (Guinea pig)

產品貨號	產品名稱	來源
CSB-YP846073GU CSB-EP846073GU CSB-BP846073GU CSB-MP846073GU CSB-EP846073GU-B	Recombinant Cavia porcellus Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Sigmodon hispidus (Hispid cotton rat)

產品貨號	產品名稱	來源
CSB-YP856338SZK CSB-EP856338SZK CSB-BP856338SZK CSB-MP856338SZK CSB-EP856338SZK-B	Recombinant Sigmodon hispidus Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL12B Proteins for Equus caballus (Horse)

產品貨號	產品名稱	來源
CSB-YP893607HO CSB-EP893607HO CSB-BP893607HO CSB-MP893607HO CSB-EP893607HO-B	Recombinant Horse Interleukin-12 subunit beta (IL12B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli