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HSPA1A

HSPA1A,全稱為熱休克蛋白家族A成員1A(Heat Shock Protein Family A Member 1A),是一種重要的分子伴侶,在細胞應激反應中發揮著關鍵作用。它能夠幫助蛋白質正確折疊,修復錯誤折疊的蛋白質,并促進蛋白質復合物的形成與解離,從而維護蛋白質組的完整性。HSPA1A蛋白也參與了細胞內的信號傳導過程,影響細胞的生長、分化和凋亡。
HSPA1A蛋白的表達水平與多種疾病相關,如癌癥、神經退行性疾病和感染性疾病等。近年來,HSPA1A蛋白成為藥物研發的一個熱點,研究人員正在探索其作為治療癌癥、神經退行性疾病和感染性疾病的潛在靶點。例如,有研究顯示,HSPA1A蛋白可以抑制腫瘤細胞的增殖和轉移,并促進腫瘤細胞的凋亡。此外,HSPA1A蛋白還可以增強免疫細胞的功能,幫助身體抵抗感染。因此,HSPA1A蛋白有望成為開發新型抗癌藥物和治療感染性疾病的潛在靶點。

熱銷產品

HSPA1A/HSPA1B Recombinant Monoclonal Antibody (CSB-RA151186A0HU)

驗證數據

CSB-RA151186A0HU

Western Blot
Positive WB detected in: HEK293 whole cell lysate(30μg), U937 whole cell lysate(30μg), NIH/3T3 whole cell lysate(30μg)
All lanes: Hsp70 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 70 kDa
Observed band size: 70 kDa
Exposure time: 3min

CSB-RA151186A0HU

IHC image of CSB-RA151186A0HU diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.

CSB-RA151186A0HU

Overlay Peak curve showing Hela cells stained with CSB-RA151186A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human Heat Shock Protein 72(HSP-72) ELISA Kit (CSB-E14916h)

驗證數據

CSB-E14916h 標準曲線

貨號:CSB-E14916h

規格:96T/48T

靈敏度:0.78 ng/mL

檢測范圍:3.12 ng/mL-200 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

HSPA1A Antibodies

HSPA1A for Homo sapiens (Human)

HSPA1A ELISA Kit

HSPA1A ELISA Kit for Homo sapiens (Human)