HAVCR1

HAVCR1，全稱為hepatitis A virus cellular receptor 1，常見別名包括TIM-1和HAVCR1。該蛋白是一種Ⅰ型黏蛋白樣整合膜糖蛋白，在甲型肝炎病毒（HAV）的感染過程中扮演關(guān)鍵角色。HAVCR1作為HAV的受體，介導(dǎo)病毒與肝細(xì)胞的結(jié)合，進(jìn)而促進(jìn)病毒進(jìn)入細(xì)胞內(nèi)部。此外，HAVCR1還參與調(diào)節(jié)免疫反應(yīng)，影響炎癥和免疫調(diào)節(jié)過程。在疾病方面，HAVCR1與甲型肝炎的發(fā)病機(jī)制密切相關(guān)，同時(shí)也是寨卡病毒感染胎盤的關(guān)鍵靶點(diǎn)，與母嬰傳播密切相關(guān)。近年來，HAVCR1已成為藥物研發(fā)的重要靶點(diǎn)，針對該蛋白的抑制劑被開發(fā)用于阻斷病毒感染和疾病治療。例如，研究表明HAVCR1抑制劑可以有效阻止寨卡病毒感染胎盤，為預(yù)防先天性寨卡綜合征提供了新的治療策略。此外，HAVCR1在哮喘和過敏性疾病的發(fā)病機(jī)制中也發(fā)揮作用，相關(guān)藥物研發(fā)正在進(jìn)行中。

熱銷產(chǎn)品

Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial (CSB-MP010144HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

HAVCR1 Recombinant Monoclonal Antibody (CSB-RA974628A0HU)

驗(yàn)證數(shù)據(jù)

Western Blot
Positive WB detected in: 293T whole cell lysate(30μg), NIH/3T3 whole cell lysate(30μg), JK whole cell lysate(30μg), MCF7 whole cell lysate(30μg), Hela whole cell lysate(30μg)
All lanes: HAVCR1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/20000 dilution
Predicted band size: 50-55 kDa
Observed band size: 55 kDa
Exposure time：10s

Human Kidney injury molecule 1,Kim-1 ELISA Kit (CSB-E08807h)

驗(yàn)證數(shù)據(jù)

貨號：CSB-E08807h

規(guī)格：96T/48T

靈敏度：0.043 ng/mL

檢測范圍：0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

HAVCR1 Antibody

HAVCR1 Protein

HAVCR1 ELISA Kit

HAVCR1 Antibodies

HAVCR1 for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA17109A0Rb	Havcr1 Antibody	Mouse	ELISA, IHC

HAVCR1 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA09995A0Rb	HAVCR1 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA090386	HAVCR1 Antibody	Human	ELISA,IHC
CSB-PA913997	HAVCR1 Antibody	Human	ELISA,WB
CSB-RA974628A0HU	HAVCR1 Recombinant Monoclonal Antibody	Human, Mouse	ELISA, WB
CSB-RA010144MA1HU	HAVCR1 Recombinant Monoclonal Antibody	Human	ELISA, IHC

HAVCR1 Proteins

HAVCR1 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP010144RA1 CSB-EP010144RA1 CSB-BP010144RA1 CSB-MP010144RA1 CSB-EP010144RA1-B	Recombinant Rat Hepatitis A virus cellular receptor 1 homolog (Havcr1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF010144RA	Recombinant Rat Hepatitis A virus cellular receptor 1 homolog (Havcr1)	in vitro E.coli expression system

HAVCR1 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP010144DSU1 CSB-EP010144DSU1 CSB-BP010144DSU1 CSB-MP010144DSU1 CSB-EP010144DSU1-B	Recombinant Chlorocebus aethiops Hepatitis A virus cellular receptor 1 (HAVCR1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF010144DSU	Recombinant Chlorocebus aethiops Hepatitis A virus cellular receptor 1 (HAVCR1)	in vitro E.coli expression system

HAVCR1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP010144HU CSB-EP010144HU CSB-BP010144HU CSB-EP010144HU-B	Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-MP010144HU	Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial	Mammalian cell

HAVCR1 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP735580MO CSB-EP735580MO CSB-BP735580MO CSB-MP735580MO CSB-EP735580MO-B	Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog (Havcr1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP735580MO	Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog (Havcr1), partial	E.coli