GPX1
谷胱甘肽過氧化物酶1（Glutathione peroxidase 1），簡稱GPX1，主要功能是清除細(xì)胞內(nèi)過氧化氫和脂質(zhì)過氧化物，維持氧化還原平衡，防止活性氧（ROS）積累導(dǎo)致的細(xì)胞損傷。GPX1基因突變可能導(dǎo)致酶活性降低，使細(xì)胞更容易受到氧化應(yīng)激的傷害，與多種疾病相關(guān)，包括心血管疾病、神經(jīng)退行性疾病（如阿爾茨海默病和帕金森病）、糖尿病和癌癥。GPX1的表達(dá)受多種因素調(diào)節(jié)，包括硒的攝入量（因?yàn)槲荊PX1活性中心的必需元素）、氧化應(yīng)激水平和轉(zhuǎn)錄因子（如Nrf2）。在癌癥中，GPX1的作用較為復(fù)雜，一方面其抗氧化功能可能抑制腫瘤發(fā)生，但在某些情況下，GPX1的高表達(dá)可能幫助癌細(xì)胞抵抗化療藥物的氧化殺傷，促進(jìn)腫瘤進(jìn)展。此外，GPX1與其他抗氧化酶（如超氧化物歧化酶SOD和過氧化氫酶CAT）協(xié)同作用，構(gòu)成細(xì)胞的抗氧化防御網(wǎng)絡(luò)。GPX1還與炎癥反應(yīng)相關(guān)，因?yàn)檠趸瘧?yīng)激是炎癥的重要誘因。總之，GPX1在維持細(xì)胞氧化還原平衡中起關(guān)鍵作用，其表達(dá)異常與多種病理過程密切相關(guān)。目前，針對(duì)GPX1的藥物研發(fā)主要集中在抗氧化劑和炎癥調(diào)節(jié)劑等方面，以期為相關(guān)疾病的治療提供新的策略。
熱銷產(chǎn)品
Recombinant Human Glutathione peroxidase 1 (GPX1) (U49S) (CSB-EP009866HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
GPX1 Antibody (CSB-PA009866KA01HU)
驗(yàn)證數(shù)據(jù)
Western blot analysis of extracts of various cell lines, using GPX1 antibody.
Human Glutathione peroxidase 1(GPX1) ELISA kit (CSB-EL009866HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL009866HU
規(guī)格：96T/48T
靈敏度：3.9 μU/mL
檢測(cè)范圍：15.6 μU/mL-1000 μU/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
GPX1 Antibodies
GPX1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA009866KA01HU | GPX1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-RA009866A0HU | GPX1 Recombinant Monoclonal Antibody | Human | ELISA |
GPX1 Proteins
GPX1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866MO CSB-EP009866MO CSB-BP009866MO CSB-MP009866MO CSB-EP009866MO-B |
Recombinant Mouse Glutathione peroxidase 1 (Gpx1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866RB CSB-EP009866RB CSB-BP009866RB CSB-MP009866RB CSB-EP009866RB-B |
Recombinant Rabbit Glutathione peroxidase 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866HU CSB-BP009866HU CSB-MP009866HU CSB-EP009866HU-B |
Recombinant Human Glutathione peroxidase 1 (GPX1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP009866HU | Recombinant Human Glutathione peroxidase 1 (GPX1) (U49S) | E.coli |
| CSB-EP009866HUa2 | Recombinant Human Glutathione peroxidase 1 (GPX1) (U49S) | E.coli |
GPX1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866BO CSB-EP009866BO CSB-BP009866BO CSB-MP009866BO CSB-EP009866BO-B |
Recombinant Bovine Glutathione peroxidase 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker\'s yeast)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866SVG CSB-EP009866SVG CSB-BP009866SVG CSB-MP009866SVG CSB-EP009866SVG-B |
Recombinant Saccharomyces cerevisiae Glutathione peroxidase-like peroxiredoxin 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866RA CSB-EP009866RA CSB-BP009866RA CSB-MP009866RA CSB-EP009866RA-B |
Recombinant Rat Glutathione peroxidase 1 (Gpx1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Synechocystis sp. (strain PCC 6803 / Kazusa)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP300400SSQ CSB-EP300400SSQ CSB-BP300400SSQ CSB-MP300400SSQ CSB-EP300400SSQ-B |
Recombinant Synechocystis sp. Putative glutathione peroxidase (slr1171) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Schistosoma mansoni (Blood fluke)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP308789SXQ CSB-EP308789SXQ CSB-BP308789SXQ CSB-MP308789SXQ CSB-EP308789SXQ-B |
Recombinant Schistosoma mansoni Glutathione peroxidase (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Arabidopsis thaliana (Mouse-ear cress)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP346343DOA CSB-EP346343DOA CSB-BP346343DOA CSB-MP346343DOA CSB-EP346343DOA-B |
Recombinant Arabidopsis thaliana Phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP528886SXV CSB-EP528886SXV CSB-BP528886SXV CSB-MP528886SXV CSB-EP528886SXV-B |
Recombinant Schizosaccharomyces pombe Glutathione peroxidase (gpx1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Macaca fuscata fuscata (Japanese macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866MMX CSB-EP009866MMX CSB-BP009866MMX CSB-MP009866MMX CSB-EP009866MMX-B |
Recombinant Macaca fuscata fuscata Glutathione peroxidase 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866PI CSB-EP009866PI CSB-BP009866PI CSB-MP009866PI CSB-EP009866PI-B |
Recombinant Pig Glutathione peroxidase 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866EQV CSB-EP009866EQV CSB-BP009866EQV CSB-MP009866EQV CSB-EP009866EQV-B |
Recombinant Pan troglodytes Glutathione peroxidase 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Callithrix jacchus (White-tufted-ear marmoset)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866CYL CSB-EP009866CYL CSB-BP009866CYL CSB-MP009866CYL CSB-EP009866CYL-B |
Recombinant Callithrix jacchus Glutathione peroxidase 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Hylobates lar (Common gibbon)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866HXW CSB-EP009866HXW CSB-BP009866HXW CSB-MP009866HXW CSB-EP009866HXW-B |
Recombinant Hylobates lar Glutathione peroxidase 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Cebus apella (Brown-capped capuchin)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866DQU CSB-EP009866DQU CSB-BP009866DQU CSB-MP009866DQU CSB-EP009866DQU-B |
Recombinant Cebus apella Glutathione peroxidase 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Pongo pygmaeus (Bornean orangutan)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009866EXP CSB-EP009866EXP CSB-BP009866EXP CSB-MP009866EXP CSB-EP009866EXP-B |
Recombinant Pongo pygmaeus Glutathione peroxidase 1 (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 Proteins for Molluscum contagiosum virus subtype 1 (MOCV) (MCVI)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP836519MHI CSB-EP836519MHI CSB-BP836519MHI CSB-MP836519MHI CSB-EP836519MHI-B |
Recombinant Molluscum contagiosum virus subtype 1 Glutathione peroxidase (GPX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPX1 ELISA Kit
GPX1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL009866HU | Human Glutathione peroxidase 1(GPX1) ELISA kit | serum, plasma, tissue homogenates | 3.9 μU/mL |
GPX1 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E12146r | Rat Glutathione Peroxidase (GSH-PX) ELISA kit | serum, plasma, tissue homogenates | 3.12 mIU/mL |
GPX1 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13068m | Mouse glutathione peroxidase(GSH-Px)ELISA Kit | serum, plasma, tissue homogenates | 7.8 U/mL |
