GHSR
GHS-R，即生長(zhǎng)激素促釋放激素受體，別名Growth hormone secretagogue receptor type 1、GHS-R、GH-releasing peptide receptor。它是一種G蛋白偶聯(lián)受體，主要在大腦、胃腸道和胰腺等組織中表達(dá)。GHS-R的作用機(jī)制是通過(guò)與生長(zhǎng)激素促釋放激素（GHRH）結(jié)合，激活Gαs蛋白，進(jìn)而促進(jìn)腺苷酸環(huán)化酶（AC）的活性，導(dǎo)致cAMP水平上升，激活蛋白激酶A（PKA），最終促進(jìn)生長(zhǎng)激素（GH）的釋放。它不僅參與調(diào)節(jié)生長(zhǎng)激素的分泌，影響生長(zhǎng)發(fā)育，還與能量代謝、食欲控制、應(yīng)激反應(yīng)等多種生理過(guò)程有關(guān)。此外，GHS-R的活性也與某些疾病相關(guān)，例如肥胖和生長(zhǎng)激素缺乏癥。因此，GHS-R是內(nèi)分泌學(xué)和代謝疾病研究中的一個(gè)重要靶點(diǎn)，針對(duì)GHS-R的藥物開(kāi)發(fā)有助于治療相關(guān)疾病。
熱銷(xiāo)產(chǎn)品
驗(yàn)證數(shù)據(jù)
Western blot analysis of 1) Rat LiverTissue, 2)Jurkat with Ghrelin Receptor Rabbit pAb diluted at 1:2,000.
Immunohistochemical analysis of paraffin-embedded Human BrainTissue using Ghrelin Receptor Rabbit pAb diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using Ghrelin Receptor Rabbit pAb diluted at 1:200.
GHSR Antibodies
GHSR for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA545380 | GHSR Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA562807 | GHSR Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA450853 | GHSR Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA842164LA01HU | GHSR Antibody | Human | ELISA, IHC |
| CSB-PA842164LB01HU | GHSR Antibody, HRP conjugated | Human | ELISA |
| CSB-PA842164LC01HU | GHSR Antibody, FITC conjugated | Human | |
| CSB-PA842164LD01HU | GHSR Antibody, Biotin conjugated | Human | ELISA |
GHSR Proteins
GHSR Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP009416RB1 CSB-EP009416RB1 CSB-BP009416RB1 CSB-MP009416RB1 CSB-EP009416RB1-B |
Recombinant Rabbit Growth hormone secretagogue receptor type 1 (GHSR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009416RB | Recombinant Rabbit Growth hormone secretagogue receptor type 1 (GHSR) | in vitro E.coli expression system |
GHSR Proteins for Mustela putorius furo (European domestic ferret) (Mustela furo)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP009416MOH1 CSB-EP009416MOH1 CSB-BP009416MOH1 CSB-MP009416MOH1 CSB-EP009416MOH1-B |
Recombinant Mustela putorius furo Growth hormone secretagogue receptor type 1 (GHSR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009416MOH | Recombinant Mustela putorius furo Growth hormone secretagogue receptor type 1 (GHSR) | in vitro E.coli expression system |
GHSR Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP009416RA1 CSB-EP009416RA1 CSB-BP009416RA1 CSB-MP009416RA1 CSB-EP009416RA1-B |
Recombinant Rat Growth hormone secretagogue receptor type 1 (Ghsr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009416RA | Recombinant Rat Growth hormone secretagogue receptor type 1 (Ghsr) | in vitro E.coli expression system |
GHSR Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP842164HU1 CSB-EP842164HU1 CSB-BP842164HU1 CSB-MP842164HU1 CSB-EP842164HU1-B |
Recombinant Human Growth hormone secretagogue receptor type 1 (GHSR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF842164HU | Recombinant Human Growth hormone secretagogue receptor type 1 (GHSR) | in vitro E.coli expression system |
GHSR Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP853264PI1 CSB-EP853264PI1 CSB-BP853264PI1 CSB-MP853264PI1 CSB-EP853264PI1-B |
Recombinant Pig Growth hormone secretagogue receptor type 1 (GHSR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF853264PI | Recombinant Pig Growth hormone secretagogue receptor type 1 (GHSR) | in vitro E.coli expression system |
GHSR Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP858781MO1 CSB-EP858781MO1 CSB-BP858781MO1 CSB-MP858781MO1 CSB-EP858781MO1-B |
Recombinant Mouse Growth hormone secretagogue receptor type 1 (Ghsr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF858781MO | Recombinant Mouse Growth hormone secretagogue receptor type 1 (Ghsr) | in vitro E.coli expression system |
