FABP5

FABP5，即脂肪酸結(jié)合蛋白5，是一種廣泛存在于多種組織中的脂質(zhì)伴侶蛋白。它參與調(diào)控脂肪酸的攝取、轉(zhuǎn)運、代謝以及炎癥反應(yīng)等多種生物學(xué)過程。FABP5的作用機制涉及與長鏈不飽和脂肪酸的結(jié)合，進(jìn)而影響細(xì)胞內(nèi)的脂質(zhì)代謝和信號傳導(dǎo)。特別是在氧化應(yīng)激狀態(tài)下，F(xiàn)ABP5可以通過谷胱甘肽化修飾，促進(jìn)其核轉(zhuǎn)位，激活PPARβ/δ信號通路，抑制巨噬細(xì)胞炎癥，對急性肺損傷等炎癥性疾病具有保護(hù)作用。此外，F(xiàn)ABP5還通過調(diào)節(jié)PPARγ信號通路影響巨噬細(xì)胞的M2極化，進(jìn)而參與過敏性哮喘等免疫調(diào)節(jié)過程。FABP5的功能異常與多種疾病包括癌癥、炎癥性疾病和代謝性疾病等有關(guān)，是重要的疾病治療靶點。

熱銷產(chǎn)品

Recombinant Human Fatty acid-binding protein 5 (FABP5) (CSB-EP007946HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Human Fatty acid-binding protein, epidermal(FABP5) ELISA kit (CSB-EL007946HU)

驗證數(shù)據(jù)

貨號：CSB-EL007946HU

規(guī)格：96T/48T

靈敏度：0.195 ng/mL

檢測范圍：0.78 ng/mL-50 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

FABP5 Antibody

FABP5 Protein

FABP5 ELISA Kit

FABP5 Antibodies

FABP5 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA007946GA01HU	FABP5 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA007946ESR1HU	FABP5 Antibody	Human	ELISA, WB

FABP5 Proteins

FABP5 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP007946RA CSB-EP007946RA CSB-BP007946RA CSB-MP007946RA CSB-EP007946RA-B	Recombinant Rat Fatty acid-binding protein, epidermal (Fabp5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FABP5 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP007946BO CSB-EP007946BO CSB-BP007946BO CSB-MP007946BO CSB-EP007946BO-B	Recombinant Bovine Fatty acid-binding protein, epidermal (FABP5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli