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Your Good Partner in Biology Research

ENPP3

外核苷酸焦磷酸酶/磷酸二酯酶家族成員3是一種由ENPP3基因編碼的酶。Hiroaki在2013年的實驗中對N2a細胞進行研究,純化了存在于GnT-IX中的一種內源性抑制因子,發現其與外核苷酸焦磷酸酶/磷酸二酯酶3 (ENPP3)相同,這一結果通過質譜分析以及培養細胞中ENPP3的敲除和過表達得到了證明。動力學分析顯示,ENPP3導致的GnT-IX抑制機制是ENPP3介導的核苷酸糖供體底物UDP-GlcNAc水解,從而生成UMP(一種強效競爭性GnT-IX抑制劑)。實際上,當對細胞內的ENPP3敲除,細胞內核苷酸糖水平顯著升高,并顯示出細胞總糖基化特征的變化。除了糖基轉移酶的伴侶或其他已知調節劑外,ENPP3介導的核苷酸糖水解將對糖基轉移酶活性產生也會產生廣泛和顯著的影響,并負責改變細胞總糖基化特征和調節細胞功能。

熱銷產品

Recombinant Macaca fascicularis Ectonucleotide pyrophosphatase/phosphodiesterase 3(ENPP3),partial (Active) (CSB-MP4278MOV)

驗證數據

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ENPP3 at 2 μg/ml can bind Anti-ENPP3 recombinant antibody (CSB-RA007681MA1HU), the EC50 is 3.313-4.724 ng/mL.

Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 3(ENPP3),partial (Active)(CSB-MP007681HU)

驗證數據

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ENPP3 at 2 μg/ml can bind anti-ENPP3 recombinant antibody (CSB-RA007681MA1HU), the EC50 is 2.151-2.492 ng/mL.

ENPP3 Recombinant Monoclonal Antibody CSB-RA007681MA1HU

驗證數據

ELISA
CSB-RA007681MA1HU ELISA

The Binding Activity of Macaca fascicularis ENPP3 with Anti-ENPP3 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ENPP3 (CSB-MP4278MOV) at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 3.313-4.724 ng/mL.

ELISA
CSB-RA007681MA1HU ELISA

The Binding Activity of Huamn ENPP3 with Anti- ENPP3 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ENPP3(CSB-MP007681HU) at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 2.151-2.492 ng/mL

FC
CSB-RA007681MA1HU FC

Untransfected HEK293T cells (green line) and transfected Human ENPP3 HEK293T stable cells (red line) were stained with anti-ENPP3 recombinant antibody (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

HEK293T/Human ENPP3 Stable Cell Line CSB-SC007681HU

驗證數據

FC
CSB-SC007681HU FC

Untransfected HEK293T cells (green line) and transfected Human ENPP3 HEK293T Stable cells (red line) were stained with anti-ENPP3 antibody (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

ENPP3 Antibodies

ENPP3 for Homo sapiens (Human)

ENPP3 Proteins

ENPP3 Proteins for Rattus norvegicus (Rat)

ENPP3 Proteins for Bos taurus (Bovine)

ENPP3 Proteins for Homo sapiens (Human)

ENPP3 Proteins for Pongo abelii (Sumatran orangutan)

ENPP3 Proteins for Mus musculus (Mouse)

ENPP3 ELISA Kit

ENPP3 ELISA Kit for Homo sapiens (Human)