EIF2AK4
EIF2AK4，也稱為eIF-2-alpha kinase GCN2，通常被稱為GCN2，是一種代謝壓力感應(yīng)蛋白激酶，負(fù)責(zé)磷酸化eIF-2-alpha/EIF2S1的α亞基。EIF2AK4在細(xì)胞應(yīng)激反應(yīng)中發(fā)揮關(guān)鍵作用，特別是在氨基酸供應(yīng)不足的情況下。它與多種疾病相關(guān)，包括癌癥，并且是藥物研發(fā)的熱點(diǎn)靶點(diǎn)。目前，針對(duì)EIF2AK4的藥物研發(fā)主要集中在開(kāi)發(fā)小分子調(diào)節(jié)劑，以治療實(shí)體瘤等疾病。
熱銷產(chǎn)品
EIF2AK4 Antibody (CSB-PA868396ESR1HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA868396ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA868396ESR1HU at dilution of 1:100
EIF2AK4 Antibodies
EIF2AK4 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007513GA01HU | EIF2AK4 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA868396ESR1HU | EIF2AK4 Antibody | Human | ELISA, IHC |
| CSB-PA868396ESR2HU | EIF2AK4 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA010224 | Phospho-EIF2AK4 (T899) Antibody | Human,Mouse | IHC, ELISA |
| CSB-PA010225 | EIF2AK4 Antibody | Human,Mouse | IHC, ELISA |
| CSB-PA555295 | EIF2AK4 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA554018 | EIF2AK4 Antibody | Human,Mouse | ELISA,IHC |
EIF2AK4 Proteins
EIF2AK4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP868396HU CSB-EP868396HU CSB-BP868396HU CSB-MP868396HU CSB-EP868396HU-B |
Recombinant Human Eukaryotic translation initiation factor 2-alpha kinase 4 (EIF2AK4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EIF2AK4 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP879465MO CSB-EP879465MO CSB-BP879465MO CSB-MP879465MO CSB-EP879465MO-B |
Recombinant Mouse Eukaryotic translation initiation factor 2-alpha kinase 4 (Eif2ak4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
