CCN2
CCN2，即結(jié)締組織生長因子，別名CTGF。它是一種在多種細(xì)胞類型中表達(dá)的蛋白質(zhì)，尤其在心臟、肺、肝、腎和實(shí)體器官移植中發(fā)揮作用。CCN2在細(xì)胞增殖、分化、粘附和血管生成等生物過程中起調(diào)控作用，同時(shí)參與腫瘤發(fā)展、組織纖維化等多種病理過程。CCN2的作用機(jī)制涉及與細(xì)胞表面的整合素受體結(jié)合，激活如FAK信號通路，進(jìn)而影響細(xì)胞行為和代謝。CCN2在胚胎發(fā)育、組織再生、纖維化反應(yīng)以及腫瘤微環(huán)境中扮演重要角色。其異常表達(dá)與多種疾病的發(fā)生發(fā)展相關(guān)，包括纖維化疾病、心血管疾病和癌癥等，因此CCN2也是藥物開發(fā)的重要靶點(diǎn)之一。
熱銷產(chǎn)品
Recombinant Macaca mulatta CCN family member 2 (CCN2) (Active) (CSB-MP5112MOW)
驗(yàn)證數(shù)據(jù)
Activity
Measured by its binding ability in a functional ELISA. Immobilized Rhesus macaque CTGF at 1 μg/ml can bind Anti-CTGF recombinant antibody (CSB-RA006147MA2HU). The EC50 is 0.6886-0.7825 ng/mL.
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Recombinant Human CCN family member 2 (CCN2), partial (CSB-EP006147HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CTGF Antibody (CSB-PA09429A0Rb)
驗(yàn)證數(shù)據(jù)
Immunofluorescent analysis of HepG2 cells using CSB-PA09429A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA09429A0Rb at dilution of 1:100
Human connective tissue growth factor (CTGF) ELISA kit (CSB-E07875h)
驗(yàn)證數(shù)據(jù)
貨號：CSB-E07875h
規(guī)格：96T/48T
靈敏度：1.875 pg/mL
檢測范圍：3.75 pg/mL-120 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CCN2 Antibodies
CCN2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA09429A0Rb | CTGF Antibody | Human | ELISA, IHC, IF |
| CSB-PA060417 | CTGF Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CCN2 Proteins
CCN2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP006147HU1 | Recombinant Human CCN family member 2 (CCN2), partial | E.coli |
| CSB-YP006147HU CSB-BP006147HU CSB-MP006147HU CSB-EP006147HU-B |
Recombinant Human CCN family member 2 (CCN2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006147HU | Recombinant Human CCN family member 2 (CCN2) | E.coli |
CCN2 ELISA Kit
CCN2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07875h | Human connective tissue growth factor (CTGF) ELISA kit | serum, plasma, tissue homogenates | 1.875 pg/mL |
