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Your Good Partner in Biology Research

AURKB

AURKB,即極光激酶B,別名AIK2、AIM1、ARK2、AurB、IPL1、STK5、AIM-1、ARK-2、STK-1、STK12、PPP1R48、aurkb-sv1、aurkb-sv2等。它來源于細胞內的基因編碼,是極光激酶家族的一員。AURKB在細胞有絲分裂過程中發(fā)揮關鍵作用,通過磷酸化多種蛋白質底物來調控染色體的凝聚、紡錘體的組裝以及細胞周期的正確進展。其作用機制確保了細胞分裂的準確性和時序性。在生物學上,AURKB的異常表達與多種癌癥的發(fā)生和發(fā)展密切相關,因此成為癌癥研究中的熱點。

熱銷產(chǎn)品

AURKB Antibody (CSB-PA002458EA01HU)

驗證數(shù)據(jù)

CSB-PA002458EA01HU

Immunofluorescence staining of Hela cells with CSB-PA002458EA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA002458EA01HU

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA002458EA01HU at dilution of 1:100

CSB-PA002458EA01HU

Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA002458EA01HU at dilution of 1:100

AURKB Antibodies

AURKB for Homo sapiens (Human)

AURKB Proteins

AURKB Proteins for Homo sapiens (Human)