ASGR1
ASGR1，即肝素結合生長因子相關受體1，別名肝素結合蛋白1（HBP1）、肝素結合生長因子受體（HBGR）。ASGR1是一種主要表達在肝臟的細胞表面受體，由人體細胞自身的基因編碼。它的作用機制涉及到與多種配體的結合，包括肝素結合生長因子（HB-EGF）、肝素以及某些脂蛋白等。ASGR1通過與這些配體結合，參與調節細胞增殖、分化和遷移等過程，同時也在脂質代謝和免疫反應中發揮作用。ASGR1在生物學上的意義主要體現在其對肝臟功能的調節作用。它參與了肝臟對脂質的攝取和代謝，特別是低密度脂蛋白（LDL）的清除。此外，ASGR1還與肝臟的再生能力有關，它通過促進肝細胞的增殖來參與肝臟損傷后的修復過程。在病理狀態下，ASGR1的功能異常可能與某些肝臟疾病，如非酒精性脂肪肝病（NAFLD）和肝纖維化等有關。因此，ASGR1是肝病研究和治療中的一個潛在靶點。
熱銷產品
Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial (CSB-MP002207RA1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ASGR1 Antibody (CSB-PA17469A0Rb)
驗證數據
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA17469A0Rb at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA17469A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
ASGR1 Antibodies
ASGR1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA17469D0Rb | ASGR1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA17469B0Rb | ASGR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA002207GA01HU | ASGR1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA17469C0Rb | ASGR1 Antibody, FITC conjugated | Human | |
| CSB-PA17469A0Rb | ASGR1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA186229 | ASGR1 Antibody | Human | ELISA,WB,IHC |
ASGR1 Proteins
ASGR1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002207MO | Recombinant Mouse Asialoglycoprotein receptor 1 (Asgr1), partial | Yeast |
| CSB-EP002207MO | Recombinant Mouse Asialoglycoprotein receptor 1 (Asgr1), partial | E.coli |
| CSB-CF002207MO(A4) | Recombinant Mouse Asialoglycoprotein receptor 1 (Asgr1) | in vitro E.coli expression system |
ASGR1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002207HU CSB-BP002207HU CSB-MP002207HU CSB-EP002207HU-B |
Recombinant Human Asialoglycoprotein receptor 1 (ASGR1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP002207HU | Recombinant Human Asialoglycoprotein receptor 1 (ASGR1), partial | E.coli |
| CSB-CF002207HU(A4) | Recombinant Human Asialoglycoprotein receptor 1 (ASGR1) | in vitro E.coli expression system |
ASGR1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002207RA1 CSB-EP002207RA1-B |
Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | Yeast In Vivo Biotinylation in E.coli |
| CSB-CF002207RA | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1) | in vitro E.coli expression system |
| CSB-BP002207RA1 | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | Baculovirus |
| CSB-MP002207RA1 | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | Mammalian cell |
| CSB-EP002207RA1 | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | E.coli |
ASGR1 Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002207PYX CSB-EP002207PYX CSB-BP002207PYX CSB-MP002207PYX CSB-EP002207PYX-B |
Recombinant Pongo abelii Asialoglycoprotein receptor 1 (ASGR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASGR1 ELISA Kit
ASGR1 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09130h | Human asialoglyco protein receptor,ASGPR ELISA Kit | serum, plasma, tissue homogenates | 7.8 ng/mL |
