APOL1

APOL1，即載脂蛋白L1，別名APOL、APO-L、FSGS4、APOL-I，是一種由人類基因編碼的分泌型高密度脂蛋白（HDL）成分，主要在肝臟合成，也在其他多種組織中表達。
APOL1的作用機制涉及其在全身脂質交換和運輸中的功能，以及從外周細胞到肝臟的反向膽固醇轉運。APOL1還能與載脂蛋白A-I結合，參與血漿中大部分膽固醇酯的形成，并促進膽固醇從細胞中的流出。
APOL1具有保護人類免受非洲錐蟲感染的先天免疫功能，但某些APOL1基因變異與非糖尿病性腎病（如FSGS和HIVAN）的風險增加有關，這些變異在撒哈拉以南非洲和非洲散居人群中高度流行。APOL1的這些功能和變異對全球健康差異有顯著影響，尤其是在非洲血統人群中。

熱銷產品

APOL1 Recombinant Monoclonal Antibody (CSB-RA966671A0HU)

驗證數據

Overlay Peak curve showing HepG2 cells stained with CSB-RA966671A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*10⁶cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*10⁶cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human Apolipoprotein L1(APOL1) ELISA kit (CSB-EL001940HU)

驗證數據

貨號：CSB-EL001940HU

規格：96T/48T

靈敏度：1.95 ng/mL

檢測范圍：7.81 ng/mL-500 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

APOL1 Antibody

APOL1 Protein

APOL1 ELISA Kit

APOL1 Antibodies

APOL1 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA001940GA01HU	APOL1 Antibody	Human	ELISA,WB,IHC
CSB-PA001940ESR1HU	APOL1 Antibody	Human	ELISA, IHC
CSB-PA001940ESR2HU	APOL1 Antibody	Human	ELISA, WB, IHC
CSB-PA923087	APOL1 Antibody	Human	ELISA,WB
CSB-PA000906	APOL1 Antibody	Human	WB, IHC, ELISA
CSB-PA082663	APOL1 Antibody	Human	ELISA,WB,IHC
CSB-PA199459	APOL1 Antibody	Human	ELISA,WB,IHC
CSB-RA966671A0HU	APOL1 Recombinant Monoclonal Antibody	Human	ELISA, FC

APOL1 Proteins

APOL1 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP001940HU CSB-EP001940HU CSB-BP001940HU CSB-MP001940HU CSB-EP001940HU-B	Recombinant Human Apolipoprotein L1 (APOL1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli