APOE

APOE，即載脂蛋白E，別名 AD2、APOEA、LDLCQ5、LPG。APOE是一種多態(tài)性蛋白，由肝臟、小腸和大腦等組織產(chǎn)生，主要功能是結(jié)合脂質(zhì)并形成脂蛋白顆粒，介導(dǎo)脂質(zhì)在體內(nèi)的運(yùn)輸和代謝。APOE的作用機(jī)制涉及與多種細(xì)胞表面受體的相互作用，如低密度脂蛋白受體（LDLR）、清道夫受體BI（SR-BI）等，通過這些受體介導(dǎo)脂蛋白的內(nèi)吞和脂質(zhì)的細(xì)胞內(nèi)運(yùn)輸。APOE4是阿爾茨海默病最強(qiáng)的遺傳風(fēng)險(xiǎn)因子之一，其與某些免疫細(xì)胞表面的受體LilrB3特異性結(jié)合，可能通過干擾小膠質(zhì)細(xì)胞的吞噬功能，促進(jìn)β-淀粉樣蛋白（Aβ）沉積，從而增加阿爾茨海默病的發(fā)病風(fēng)險(xiǎn)。APOE不僅在脂質(zhì)代謝中發(fā)揮關(guān)鍵作用，還與多種疾病的發(fā)生發(fā)展密切相關(guān)。APOE的這些多態(tài)性為研究脂質(zhì)代謝、神經(jīng)系統(tǒng)疾病以及開發(fā)新的治療策略提供了重要的分子基礎(chǔ)。

熱銷產(chǎn)品

APOE Antibody (CSB-PA07599A0Rb)

驗(yàn)證數(shù)據(jù)

Immunofluorescence staining of HepG2 cells with CSB-PA07599A0Rb at 1:333, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

IHC image of CSB-PA07599A0Rb diluted at 1:1000 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human apolipoprotein E (Apo-E) ELISA Kit (CSB-E09748h)

驗(yàn)證數(shù)據(jù)

貨號(hào)：CSB-E09748h

規(guī)格：96T/48T

靈敏度：3.9 ng/mL

檢測(cè)范圍：15.62 ng/mL-1000 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

APOE Antibody

APOE Protein

APOE ELISA Kit

APOE Antibodies

APOE for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA001936LC01MO	Apoe Antibody, FITC conjugated	Mouse
CSB-PA001936LA01MO	Apoe Antibody	Mouse	ELISA, WB
CSB-PA001936LD01MO	Apoe Antibody, Biotin conjugated	Mouse	ELISA
CSB-PA001936LB01MO	Apoe Antibody, HRP conjugated	Mouse	ELISA

APOE for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA227407	APOE Antibody	Human	ELISA,WB
CSB-PA009485	APOE Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA009486	APOE Antibody	Human	WB, ELISA
CSB-PA07599A0Rb	APOE Antibody	Human	ELISA, IHC, IF
CSB-PA07599B0Rb	APOE Antibody, HRP conjugated	Human	ELISA
CSB-PA07599C0Rb	APOE Antibody, FITC conjugated	Human
CSB-PA07599D0Rb	APOE Antibody, Biotin conjugated	Human	ELISA

APOE Proteins

APOE Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936RB CSB-BP001936RB CSB-MP001936RB CSB-EP001936RB-B	Recombinant Rabbit Apolipoprotein E (APOE)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP001936RB	Recombinant Rabbit Apolipoprotein E (APOE), partial	E.coli
CSB-EP001936RBb3	Recombinant Rabbit Apolipoprotein E (APOE), partial	E.coli
CSB-EP001936RBb7	Recombinant Rabbit Apolipoprotein E (APOE), partial	E.coli

APOE Proteins for Sus scrofa (Pig)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936PI CSB-EP001936PI CSB-BP001936PI CSB-MP001936PI CSB-EP001936PI-B	Recombinant Pig Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936DO CSB-BP001936DO CSB-MP001936DO CSB-EP001936DO-B	Recombinant Dog Apolipoprotein E (APOE)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Cavia porcellus (Guinea pig)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936GU CSB-EP001936GU CSB-BP001936GU CSB-MP001936GU CSB-EP001936GU-B	Recombinant Guinea pig Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936HU CSB-EP001936HU CSB-BP001936HU CSB-EP001936HU-B	Recombinant Human Apolipoprotein E (APOE)	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli

APOE Proteins for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936MO	Recombinant Mouse Apolipoprotein E (Apoe)	Yeast
CSB-EP001936MO	Recombinant Mouse Apolipoprotein E (Apoe)	E.coli
CSB-BP001936MO	Recombinant Mouse Apolipoprotein E (Apoe)	Baculovirus
CSB-MP001936MO	Recombinant Mouse Apolipoprotein E (Apoe)	Mammalian cell
CSB-EP001936MOc7	Recombinant Mouse Apolipoprotein E (Apoe)	E.coli

APOE Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936MOV CSB-BP001936MOV CSB-MP001936MOV CSB-EP001936MOV-B	Recombinant Macaca fascicularis Apolipoprotein E (APOE)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936RA CSB-BP001936RA CSB-MP001936RA CSB-EP001936RA-B	Recombinant Rat Apolipoprotein E (Apoe)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Papio anubis (Olive baboon)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936ERI CSB-EP001936ERI CSB-BP001936ERI CSB-MP001936ERI CSB-EP001936ERI-B	Recombinant Papio anubis Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Ovis aries (Sheep)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936SH CSB-EP001936SH CSB-BP001936SH CSB-MP001936SH CSB-EP001936SH-B	Recombinant Sheep Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Zalophus californianus (California sealion)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936ZAC CSB-EP001936ZAC CSB-BP001936ZAC CSB-MP001936ZAC CSB-EP001936ZAC-B	Recombinant Zalophus californianus Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Gorilla gorilla gorilla (Lowland gorilla)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936GGZ CSB-EP001936GGZ CSB-BP001936GGZ CSB-MP001936GGZ CSB-EP001936GGZ-B	Recombinant Gorilla gorilla gorilla Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Hylobates lar (Common gibbon)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936HXW CSB-EP001936HXW CSB-BP001936HXW CSB-MP001936HXW CSB-EP001936HXW-B	Recombinant Hylobates lar Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Tupaia glis (Tree shrew)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936TJH CSB-EP001936TJH CSB-BP001936TJH CSB-MP001936TJH CSB-EP001936TJH-B	Recombinant Tupaia glis Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Pan troglodytes (Chimpanzee)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936EQV CSB-EP001936EQV CSB-BP001936EQV CSB-MP001936EQV CSB-EP001936EQV-B	Recombinant Pan troglodytes Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Pongo pygmaeus (Bornean orangutan)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936EXP CSB-EP001936EXP CSB-BP001936EXP CSB-MP001936EXP CSB-EP001936EXP-B	Recombinant Pongo pygmaeus Apolipoprotein E (APOE)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Macaca mulatta (Rhesus macaque)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936MOW CSB-BP001936MOW CSB-MP001936MOW CSB-EP001936MOW-B	Recombinant Macaca mulatta Apolipoprotein E (APOE)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

APOE Proteins for Saimiri sciureus (Common squirrel monkey)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP001936SWD CSB-EP001936SWD CSB-BP001936SWD CSB-MP001936SWD CSB-EP001936SWD-B	Recombinant Saimiri sciureus Apolipoprotein E (APOE)partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli