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  4. Recombinant Mycobacterium tuberculosis Probable cutinase Rv1984c (Rv1984c)

Recombinant Mycobacterium tuberculosis Probable cutinase Rv1984c (Rv1984c)

In Stock
  • 中文名稱：
    結核分枝桿菌Rv1984c重組蛋白
  • 品名簡稱：
    Recombinant Mycobacterium tuberculosis Rv1984c protein
  • 貨號：
    CSB-EP351343MVZ
  • 說明書：
  • 規格：
    ￥2328
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    Rv1984c
  • Uniprot No.：
  • 別名：
    Rv1984c; MTCY39.35Probable cutinase Rv1984c; EC 3.1.1.74
  • 種屬：
    Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
  • 蛋白長度：
    Full Length of Mature Protein
  • 來源：
    E.coli
  • 分子量：
    38.7kDa
  • 表達區域：
    33-217aa
  • 氨基酸序列
    DPCSDIAVVFARGTHQASGLGDVGEAFVDSLTSQVGGRSIGVYAVNYPASDDYRASASNGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTSAMPPAVADHVAAVALFGEPSSGFSSMLWGGGSLPTIGPLYSSKTINLCAPDDPICTGGGNIMAHVSYVQSGMTSQAATFAANRLDHAG
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Tris-based buffer,50% glycerol
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Shows esterase activity, with a preference for short- and medium-chain fatty acids. Has also weak lipase activity, but does not exhibit cutinase activity. Hydrolyzes various esters, including pNP-butyrate (C4), pNP-valerate (C5), pNP-hexanoate (C6), pNP-octanoate (C8) and pNP-decanoate (C10). Can use pNP-laurate (C12) and pNP-myristate (C14), with lower efficiency. Can also hydrolyze monocaprylin and triolein, with a slow turnover.; Induces a strong delayed-type hypersensitivity (DTH) response in animal model of tuberculosis, cellular and humoral immune responses. Induces interferon-gamma (IFN-gamma) release in animal models and in human TB patients. Also induces IL-12 responses in mouse model.
  • 基因功能參考文獻：
    1. TB reactivation triggers an immune response against these antigens Cut4 and CFP21 PMID: 29709002
    2. The amino acid residues involved in substrate specificity and cytotoxicity of Cfp21 from Mycobacterium tuberculosis have been identified. PMID: 23843969
    3. CFP21 and MPT64 (immunogenic protein MPT64) fusion protein stimulate higher level of interferon (IFN)-gamma in tuberculin skin test (TST)-positive healthy population than in TST-negative healthy population. PMID: 21340709
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Cutinase family
  • 數據庫鏈接：

    KEGG: mtu:Rv1984c

    STRING: 83332.Rv1984c