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Mouse Apolipoprotein A-I-binding protein(APOA1BP) ELISA kit

  • 中文名稱:
    小鼠載脂蛋白A-I結合蛋白(APOA1BP)酶聯免疫試劑盒
  • 貨號:
    CSB-EL001914MO
  • 規格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 促銷:
  • 其他:

產品詳情

  • 產品描述:
    小鼠載脂蛋白A-I結合蛋白(APOA1BP)酶聯免疫試劑盒(CSB-EL001914MO)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的APOA1BP含量。試劑盒檢測范圍為9.38 pg/ml-600 pg/ml,適用于脂代謝機制研究、動脈粥樣硬化模型評估、肝臟功能分析等基礎科研領域。為探索脂質代謝相關信號通路及疾病模型研究提供可靠工具。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    Naxe ELISA Kit; Aibp ELISA Kit; Apoa1bp ELISA Kit; NAD(P)H-hydrate epimerase ELISA Kit; EC 5.1.99.6 ELISA Kit; Apolipoprotein A-I-binding protein ELISA Kit; AI-BP ELISA Kit; NAD(P)HX epimerase ELISA Kit
  • 縮寫:
    APOA1BP
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    9.38 pg/ml-600 pg/ml
  • 靈敏度:
    2.34 pg/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Cardiovascular
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 精密度:
     
  • 線性度:
     
  • 回收率:
     
  • 標準曲線:
     
  • 數據處理:
  • 貨期:
    3-5 working days

產品評價

靶點詳情

  • 功能:
    Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
  • 基因功能參考文獻:
    1. Loss of Apoa1bp increased vascular density and facilitated the recovery of blood vessel perfusion function in a hindlimb ischemia model. PMID: 28325782
    2. The Aibp gene encodes two different proteins, both targeted to the mitochondria (mAIBP) and cytosol (cAIBP) confirming the presence of dehydratase and epimerase in the cytosol and mitochondria. PMID: 24611804
    3. AI-BP plays an important role in capacitation possibly providing a link between protein phosphorylation and cholesterol efflux. PMID: 18202122
  • 亞細胞定位:
    Mitochondrion. Secreted. Note=In sperm, secretion gradually increases during capacitation.
  • 蛋白家族:
    NnrE/AIBP family
  • 組織特異性:
    Detected in testis and sperm (at protein level). Expressed at high levels in heart, liver, kidney, and testis.
  • 數據庫鏈接: