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  4. Human Oligodendrocyte-myelin glycoprotein(OMG) ELISA kit

Human Oligodendrocyte-myelin glycoprotein(OMG) ELISA kit

  • 中文名稱：
    人少突細胞髓磷脂糖蛋白(OMG)酶聯免疫試劑盒
  • 貨號：
    CSB-EL016334HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 促銷：
  • 其他：

產品詳情

  • 產品描述：
    人少突細胞髓磷脂糖蛋白(OMG)酶聯免疫試劑盒（CSB-EL016334HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的OMG含量。試劑盒檢測范圍為0.156 ng/mL-10 ng/mL，適用于神經科學基礎研究，如多發性硬化癥、腦白質營養不良等疾病模型的分子機制探索，亦可應用于藥物開發中髓鞘修復相關化合物的體外效果評價。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    Oligodendrocyte-myelin glycoprotein ELISA Kit; Omg ELISA Kit; OMGP ELISA Kit; OMGP_HUMAN ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.156 ng/mL-10 ng/mL
  • 靈敏度：
    0.039 ng/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Neuroscience
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human OMG in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %85
    Range %80-89
    1:2Average %97
    Range %92-102
    1:4Average %92
    Range %87-98
    1:8Average %98
    Range %94-102
  • 回收率：
    The recovery of human OMG spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 8884-92
    EDTA plasma (n=4)107102-112
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2AverageCorrected
    102.645 2.534 2.590 2.452
    51.987 2.096 2.042 1.904
    2.51.238 1.345 1.292 1.154
    1.250.754 0.765 0.760 0.622
    0.6250.429 0.446 0.438 0.300
    0.3120.312 0.324 0.318 0.180
    0.1560.221 0.226 0.224 0.086
    00.137 0.138 0.138
  • 數據處理：
  • 貨期：
    3-5 working days

引用文獻

產品評價

靶點詳情

  • 功能：
    Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
  • 基因功能參考文獻：
    1. The results do not support a relationship between the OMGP gene and the learning disability phenotype observed in neurofibromatosis type 1. PMID: 21534343
    2. novel mutations and novel polymorphisms in coding regions and 5'UTR were detected in patients with with non-syndromic mental retardation PMID: 16425041
    3. Data show that oligodendrocyte-myelin glycoprotein is downregulated in schizophrenia anterior temporal lobe revealed by shotgun proteome analysis. PMID: 19034380
  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 組織特異性：
    Oligodendrocytes and myelin of the central nervous system.
  • 數據庫鏈接：

    HGNC: 8135

    OMIM: 164345

    KEGG: hsa:4974

    STRING: 9606.ENSP00000247271

    UniGene: Hs.113874