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Bovine Interferon β,IFN-β/IFNB ELISA Kit

  • 中文名稱:
    牛β干擾素(IFN-β/IFNB)酶聯(lián)免疫試劑盒
  • 貨號:
    CSB-E13699B
  • 規(guī)格:
    96T/48T
  • 價格:
    ¥4200/¥3000
  • 促銷:
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    牛β干擾素(IFN-β/IFNB)酶聯(lián)免疫試劑盒(CSB-E13699B)為競爭法ELISA試劑盒,定量檢測樣本中的IFNB1含量。IFNB1,即干擾素β1,是一種重要的免疫調(diào)節(jié)蛋白,具有抗病毒、抗腫瘤和免疫調(diào)節(jié)等多種生物學(xué)功能。其研究機(jī)制涉及調(diào)節(jié)免疫細(xì)胞活性、抑制病毒復(fù)制和調(diào)節(jié)炎癥反應(yīng)。在病毒感染和自身免疫疾病中發(fā)揮關(guān)鍵作用。科研人員可將其應(yīng)用于畜牧病原體感染模型評估、疫苗免疫效力研究或抗病毒藥物篩選等領(lǐng)域,為探究宿主防御機(jī)制及疾病防控策略提供可靠工具。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名:
    IFNB1Interferon beta-1 ELISA Kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Bos taurus (Bovine)
  • 樣本類型:
    serum, plasma
  • 檢測范圍:
    8 pg/ml-200 pg/ml
  • 靈敏度:
    5 pg/ml
  • 反應(yīng)時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領(lǐng)域:
    Immunology
  • 測定原理:
    quantitative
  • 測定方法:
    Competitive
  • 精密度:

  • 線性度:

  • 回收率:

  • 標(biāo)準(zhǔn)曲線:

  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Has antiviral, antibacterial and anticancer activities.
  • 基因功能參考文獻(xiàn):
    1. BVDV2-E significantly increased IFN-beta activity compared to BVDV2-wt. PMID: 28432927
    2. The data confirm the involvement of EHMT2 in the epigenetic regulation of IFN-b and demonstrate the activation of a general antiviral state after EHMT2 inhibition. PMID: 26418342
    3. The authors provide evidence that ICP27 protein encoded by bovine herpesvirus type 1, a viral early protein that shuttles between the nucleus and cytoplasm inhibits transcriptional activity of two bovine IFN-beta gene promoters (IFN-beta1 and IFN-beta3). PMID: 22902481
    4. The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta promoter activity and induces IRF3 degradation. PMID: 21689696
    5. These studies provide evidence that virus infection differentially stimulates expression of the three bovine IFN-beta genes. PMID: 21316405
    6. recombinant bovine respiratory syncytial virus lacking the NS proteins, and those lacking NS2 in particular, are strong inducers of IFN-alpha/beta in bovine nasal fibroblasts and bronchoalveolar macrophages. PMID: 12857912

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  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Alpha/beta interferon family
  • 數(shù)據(jù)庫鏈接: