HCRTR1
HCRTR1，即下丘腦神經(jīng)肽orexin受體1，別名Ox1-R。攝食行為、睡眠-覺(jué)醒周期、應(yīng)激反應(yīng)等多種生理功能相關(guān)。HCRTR1的作用機(jī)制是通過(guò)與下丘腦神經(jīng)肽orexin A的結(jié)合，激活G蛋白偶聯(lián)的信號(hào)傳導(dǎo)途徑，影響下游的細(xì)胞內(nèi)信號(hào)級(jí)聯(lián)反應(yīng)。HCRTR1在調(diào)節(jié)睡眠、覺(jué)醒、能量代謝以及對(duì)應(yīng)激的響應(yīng)等方面發(fā)揮重要作用。此外，HCRTR1的功能異常與多種疾病相關(guān)，包括失眠、嗜睡癥、肥胖等，因此它也是藥物開(kāi)發(fā)中的潛在靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Orexin/Hypocretin receptor type 1 (HCRTR1), partial (CSB-YP010231HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
HCRTR1 Antibody (CSB-PA797469)
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA797469(HCRTR1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA797469(HCRTR1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
HCRTR1 Antibodies
HCRTR1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA010231GA01HU | HCRTR1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA009162 | HCRTR1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA009167 | HCRTR1 Antibody | Human,Mouse,Rat | IF, ELISA |
| CSB-PA797469 | HCRTR1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA153820 | HCRTR1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA010231HA01HU | HCRTR1 Antibody | Human | ELISA, IF |
| CSB-PA010231HB01HU | HCRTR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA010231HC01HU | HCRTR1 Antibody, FITC conjugated | Human | |
| CSB-PA010231HD01HU | HCRTR1 Antibody, Biotin conjugated | Human | ELISA |
HCRTR1 Proteins
HCRTR1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP010231MO1 CSB-EP010231MO1 CSB-BP010231MO1 CSB-MP010231MO1 CSB-EP010231MO1-B |
Recombinant Mouse Orexin/Hypocretin receptor type 1 (Hcrtr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010231MO | Recombinant Mouse Orexin/Hypocretin receptor type 1 (Hcrtr1) | in vitro E.coli expression system |
HCRTR1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP010231RA1 CSB-EP010231RA1 CSB-BP010231RA1 CSB-MP010231RA1 CSB-EP010231RA1-B |
Recombinant Rat Orexin receptor type 1 (Hcrtr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010231RA | Recombinant Rat Orexin receptor type 1 (Hcrtr1) | in vitro E.coli expression system |
HCRTR1 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP010231PI CSB-EP010231PI CSB-BP010231PI CSB-MP010231PI CSB-EP010231PI-B |
Recombinant Pig Orexin receptor type 1 (HCRTR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HCRTR1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP606357BO1 CSB-EP606357BO1 CSB-BP606357BO1 CSB-MP606357BO1 CSB-EP606357BO1-B |
Recombinant Bovine Orexin receptor type 1 (HCRTR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF606357BO | Recombinant Bovine Orexin receptor type 1 (HCRTR1) | in vitro E.coli expression system |
HCRTR1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-CF010231HU | Recombinant Human Orexin/Hypocretin receptor type 1 (HCRTR1) | in vitro E.coli expression system |
| CSB-EP010231HU1 | Recombinant Human Orexin/Hypocretin receptor type 1 (HCRTR1), partial | E.coli |
| CSB-BP010231HU1 CSB-MP010231HU1 CSB-EP010231HU1-B |
Recombinant Human Orexin/Hypocretin receptor type 1 (HCRTR1), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP010231HU1 | Recombinant Human Orexin/Hypocretin receptor type 1 (HCRTR1), partial | Yeast |
