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  4. Rat anti-Mullerian hormone (AMH) ELISA kit

Rat anti-Mullerian hormone (AMH) ELISA kit

  • 中文名稱：
    大鼠繆勒管抑制物質(zhì)/抗繆勒管激素(AMH)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-E11162r
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 促銷：
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    大鼠繆勒管抑制物質(zhì)/抗繆勒管激素(AMH)酶聯(lián)免疫試劑盒（CSB-E11162r）為競爭法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的AMH含量。AMH（抗繆勒管激素）是一種由卵巢和睪丸分泌的激素，對性別分化和生殖系統(tǒng)發(fā)育至關(guān)重要。其研究機制涉及調(diào)節(jié)生殖管道發(fā)育、抑制原始卵泡募集、影響卵巢儲備和生育能力。AMH水平與年齡、卵巢功能和生育狀況密切相關(guān)。試劑盒檢測范圍為0.2 ng/mL-15 ng/mL，適用于生殖生物學(xué)、內(nèi)分泌學(xué)等領(lǐng)域的科學(xué)研究，可用于探索性腺發(fā)育機制、評估生殖相關(guān)疾病模型中的激素水平動態(tài)變化，或用于藥物干預(yù)實驗中對AMH表達調(diào)控的效應(yīng)分析，為深入解析大鼠生殖系統(tǒng)功能提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    Amh ELISA Kit; Muellerian-inhibiting factor ELISA Kit; Anti-Muellerian hormone ELISA Kit; AMH ELISA Kit; Muellerian-inhibiting substance ELISA Kit; MIS ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Rattus norvegicus (Rat)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.2 ng/mL-15 ng/mL
  • 靈敏度：
    0.1 ng/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Competitive
  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<15%

    Three samples of known concentration were tested twenty times on one plate to assess.

    Inter-assay Precision (Precision between assays): CV%<15%

    Three samples of known concentration were tested in twenty assays to assess.

  • 標(biāo)準(zhǔn)曲線：

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

    ng/ml

    OD1

    OD2

    Average

    0

    2.179

    2.234

    2.207

    0.2

    1.752

    1.667

    1.710

    0.6

    1.411

    1.428

    1.420

    1.75

    0.823

    0.829

    0.826

    5

    0.482

    0.501

    0.491

    15

    0.264

    0.253

    0.259

  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

引用文獻

產(chǎn)品評價

靶點詳情

  • 最新研究進展：
    AMH是一種由生殖細胞產(chǎn)生的生長因子，主要參與了性腺的發(fā)育和生殖調(diào)節(jié)。最新研究表明，AMH在女性中發(fā)揮著重要的作用，如參與卵巢生長和發(fā)育、卵泡發(fā)育和成熟、排卵和孕產(chǎn)等過程。此外，AMH在生殖醫(yī)學(xué)中也被廣泛應(yīng)用于卵巢儲備功能評估和IVF治療等方面。近年來，一些新型AMH檢測技術(shù)的研究也為AMH在臨床上的應(yīng)用提供了更加準(zhǔn)確和可靠的方法。
  • 功能：
    This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
  • 基因功能參考文獻：
    1. The study uncovers a new role for AMH in regulating gonadotrope function and suggests that AMH participates in the postnatal elevation of FSH secretion in females. PMID: 27030385
    2. AMH increases GnRH-dependent LH pulsatility and secretion, supporting a central action of AMH on GnRH neurons. PMID: 26753790
    3. Resveratrol reduced antimullerian hormone levels in rat model of polycystic ovary syndrome. PMID: 25667201
    4. AMH is the first hormone/protein shown to have an inhibitory action on primordial follicle assembly. PMID: 21637711
    5. In ovaries from adult cycling rats AMH protein is localized in large primary and secondary follicles and not in primordial or small primary follicles, with its highest expression in the largest preantral follicles. PMID: 20816688
    6. Mullerian inhibiting substance regulates gonadotropin gene expression PMID: 12878721
    7. MIS inhibits regeneration of Leydig cells in ethylene dimethanesulfonate-treated rats by enhancing apoptotic cell death as well as by decreasing proliferative capacity. PMID: 14585814

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    TGF-beta family
  • 數(shù)據(jù)庫鏈接：