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  4. Monkey Brain-derived neurotrophic factor(BDNF) ELISA kit

Monkey Brain-derived neurotrophic factor(BDNF) ELISA kit

  • 中文名稱：
    猴腦源性神經營養(yǎng)因子(BDNF)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL002655RH
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥4200/￥3000
  • 促銷：
  • 其他：

產品詳情

  • 產品描述：
    猴腦源性神經營養(yǎng)因子(BDNF)酶聯(lián)免疫試劑盒（CSB-EL002655RH）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的BDNF含量。BDNF即腦源性神經營養(yǎng)因子，是神經營養(yǎng)因子家族重要成員。它在神經系統(tǒng)的發(fā)育、維持神經元存活和分化等方面發(fā)揮關鍵作用。其研究機制主要圍繞與TrkB受體結合，激活下游信號通路，對神經可塑性、學習記憶等產生影響。試劑盒檢測范圍為0.78 ng/mL-50 ng/mL，本試劑盒通過高特異性抗體對目標蛋白進行捕獲與檢測，操作流程標準化，可穩(wěn)定分析不同來源樣本的BDNF濃度差異，為神經生物學基礎研究、疾病動物模型評估或藥物干預效果驗證等科研場景提供可靠數(shù)據(jù)支持。BDNF表達水平變化常被用于神經退行性疾病、抑郁癥及認知功能相關機制的科學研究。本品僅用于科研，不用于臨床診斷，產品具體參數(shù)及操作步驟詳見產品說明書。
  • 別名：
    BDNFBrain-derived neurotrophic factor ELISA kit; BDNF) [Cleaved into: BDNF precursor form ELISA kit; ProBDNF)] ELISA kit; Fragment ELISA kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Monkey
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.78 ng/mL-50 ng/mL
  • 靈敏度：
    0.195 ng/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Cardiovascular
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/ml OD1 OD2 Average Corrected
    50 2.391 2.219 2.305 2.195
    25 1.791 1.812 1.802 1.692
    12.5 1.320 1.366 1.343 1.233
    6.25 0.801 0.845 0.823 0.713
    3.12 0.557 0.553 0.555 0.445
    1.56 0.369 0.388 0.379 0.269
    0.78 0.254 0.265 0.260 0.150
    0 0.107 0.112 0.110 　
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.; Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse.
  • 亞細胞定位：
    Secreted.; [BDNF precursor form]: Secreted.
  • 蛋白家族：
    NGF-beta family
  • 數(shù)據(jù)庫鏈接：